Results 41 to 50 of about 74,450 (290)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A Comparative Analysis of Golestan and rhymed Prose on the basis of Arabic Rhetoric [PDF]
Literary Arts, 2015 Harmonious and rhymed prose is a literary kind of speech characterized by producing music and intonation in order to conveying meaning of the context as well as possible and influencing the addressee more.
Taher Lavzheh +2 more
doaj
A Critical Approach to English Translations of Imam Ali's Instructions to Malik al-Ashtar [PDF]
Matn/Pizhūhī-i Adabī, 2004 Nahjul-Balaghah, Peak of Eloquence, ranks amongst the great literary masterpieces of mankind in both its informa• tive content and splendid style. Linguistically speaking , its delicate expressions and blossoming statements contain great ideas uttered in
salar manafi anari
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
David Ross Brower and Nature\u27s Laws [PDF]
, 2001 “We\u27re not blindly opposed to progress. We\u27re opposed to blind progress.” These words summed up the style and power of David R. Brower. Indelibly, he chiseled toe hold after toe hold on an arduous climb across the rock face of the commercial forces
Robinson, Nicholas A.
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Quss Ibn Sa’ida al-Iyadi (6th–7th cent. A.D.), Bishop of Najran: An Arabic and Islamic Cultural Hero [PDF]
, 2012 The article deals with the half-legendary Quss Ibn Sa’ida from an ancient North Arab tribe Iyad, who is believed to have been a bishop of the Yemeni city of Najran and a monk (anachorete).
Dziekan, Marek M.
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source