Results 61 to 70 of about 9,091 (303)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Muhammed Khwari (1); imitator or innovator [PDF]

open access: yesتاریخ ادبیات, 2010
Over time, literary texts have been influenced by the topics raised in the science of rhetoric, both for their aesthetic beauty and for influencing the audience.
احمد خاتمی   +1 more
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Shakespeare and Language : Reason, Eloquence and Artifice in the Renaissance

open access: yes, 2010
Why would Elizabethan audiences find Shakespeare's Porter in Macbeth so funny? And what exactly is meant by the name the 'Weird' Sisters? Jonathan Hope, in a comprehensive and fascinating study, looks at how the concept of words meant something entirely ...
Hope, Jonathan
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Voltaire’s Concept of Enlightened Eloquence

open access: yes, 1980
Near the beginning and end of his Lettres philosophiques (1734), his first major text promoting the principles of enlightenment, Voltaire gave examples of two very different kinds of eloquence.
Carr, Thomas M., Jr.
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Eloquence and Its Conditions

open access: yes, 2018
Political rhetoric generally assumes an asymmetric relationship between speaker and audience, but the rhetorical tradition has also developed resources to render this relationship more equitable.
Goodman, Rob
core   +2 more sources

The Eloquence of Mary Astell [PDF]

open access: yes, 2006
The Eloquence of Mary Astell makes an important contribution to the knowledge and understanding of the important role that women, and one woman in particular, played in the history of rhetoric. Mary Astell (1666-1731) was an unusually perceptive thinker and writer during the time of the Enlightenment.
openaire   +2 more sources

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