Results 81 to 90 of about 13,917 (336)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Emma Branche, Eloquence, 2022

open access: yes
Emma Branche on Hollins Eloquence at a Derby Show in 2022https://digitalcommons.hollins.edu/riding/1196/thumbnail ...

core   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

The gift of the gab: how eloquence works [Reseña de libro] [PDF]

open access: yes, 2017
Reseña del libro "The gift of the gab: how eloquence works" de David ...
Laborda Gil, Xavier
core   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Shakespeare and Language : Reason, Eloquence and Artifice in the Renaissance

open access: yes, 2010
Why would Elizabethan audiences find Shakespeare's Porter in Macbeth so funny? And what exactly is meant by the name the 'Weird' Sisters? Jonathan Hope, in a comprehensive and fascinating study, looks at how the concept of words meant something entirely ...
Hope, Jonathan
core   +2 more sources

Eloquence and Its Conditions [PDF]

open access: yes, 2018
Political rhetoric generally assumes an asymmetric relationship between speaker and audience, but the rhetorical tradition has also developed resources to render this relationship more equitable.
Goodman, Rob
core   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Pride, pulpit eloquence, and the rhetoric of Jonathan Swift

open access: yes, 2012
Jonathan Swift was contemptuous of the figure of the orator in his satirical writings, and yet he proved to be one of the most influential figures behind the eighteenth-century ‘elocutionary movement’ in Great Britain. His most distinctive remarks on the
Bullard, Paddy
core   +1 more source

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