Results 101 to 110 of about 1,967 (171)

tRNA Thiolation Links Translation to Stress Responses in Saccharomyces cerevisiae [PDF]

, 2014
Although tRNA modifications have been well catalogued, the precise functions of many modifications and their roles in mediating gene expression are still being elucidated.
Damon, Jadyn Rose, Pincus, David, Ploegh, Hidde   +2 more
core   +1 more source

A Novel Germline MUTYH Mutation (p.W156∗) in High‐Grade Astrocytoma, IDH Mutant

Human Mutation, Volume 2025, Issue 1, 2025.
Germline mutations in the DNA repair gene E. coli MutY homolog (MUTYH) are established predisposing factors for colorectal polyposis, colorectal carcinoma, and various extracolonic malignancies. Nevertheless, the association between MUTYH mutations and central nervous system (CNS) tumorigenesis remains poorly characterized.
Lulu Zhang, Shaoyan Xi, Lei Yuan, Ziteng Li, Xiaoyun Liu, Jiamei Gu, Shuo Li, Liyun Huang, Wanming Hu, Lingyi Fu, Aziz ur Rehman Aziz   +10 more
wiley   +1 more source

Neuronal and glial cell alterations involved in the retinal degeneration of the familial dysautonomia optic neuropathy

Glia, Volume 72, Issue 12, Page 2268-2294, December 2024.
Main Points Retinal vasculature and glial cell alterations precede the death of retinal ganglion cells in the Elp1‐deleted retina. Disruptions of the neurovascular unit (NVU) in the FD retina may exacerbate the diseased retinal state. Abstract Familial dysautonomia (FD) is a rare genetic neurodevelopmental and neurodegenerative disorder. In addition to
Anastasia Schultz, Henar Albertos‐Arranz, Xavier Sánchez Sáez, Jamie Morgan, Diane C. Darland, Alejandra Gonzalez‐Duarte, Horacio Kaufmann, Carlos E. Mendoza‐Santiesteban, Nicolás Cuenca, Frances Lefcort   +9 more
wiley   +1 more source

Higher expression of mir‐31‐5p is associated with reduced risk of head and neck keloid recurrence following surgical resection

Laryngoscope Investigative Otolaryngology, Volume 9, Issue 6, December 2024.
MicroRNA‐31‐5p expression in head and neck keloid formalin fixed paraffin embedded tissue is associated with recurrence, 1 year following treatment with surgery. MicroRNA‐3‐5p potential as a prognostic biomarker should be further investigated. Abstract Objective In this study, we aimed to evaluate mir‐31‐5p as a prognostic biomarker of keloid disease ...
Albert M. Levin, Oghenefejiro Okifo, Katherine Buhl, Takahiro Ouchi, Bianca Parker, Jessica Tan, Indrani Datta, Xiangguo Dai, Yalei Chen, Nallasivam Palanisamy, Jesse Veenstra, Shannon Carskadon, Jia Li, David Ozog, Christian E. Keller, Dhananjay Chitale, Kevin R. Bobbitt, Howard C. Crawford, Nina Steele, Qing‐Sheng Mi, Lamont R. Jones   +20 more
wiley   +1 more source

Resultados preliminares sobre la estacionalidad de la prima por liquidez en España: efectos fiscales [PDF]

, 1997
En este trabajo, estudiamos la estacionalidad de la prima por liquidez. Concretamente, tenernos en cuenta la influencia de la contratación por motivos impositivos.
Tapia Torres, Miguel Ángel
core   +1 more source

Lost in translation: How neurons cope with tRNA decoding

BioEssays, Volume 46, Issue 9, September 2024.
tRNA modifications are involved in the pathophysiology of the nervous system. Their contribution to genetic neurological disorders demands efforts to clarify their implication in translation decoding and in pathways related to protein synthesis quality control, like the unfolded protein response (UPR), ribosome quality control (RQC), and no‐go mRNA ...
Wei Guo, Stefano Russo, Francesca Tuorto
wiley   +1 more source

MEDB-42. GermlineElp1 deficiency promotes genomic instability and survival of granule neuron progenitors primed for SHH medulloblastoma pathogenesis [PDF]

, 2022
Jesús García-López, Shiekh Tanveer Ahmad, Yiran Li, Brian Gudenas, Marija Kojic, Friedrik Manz, Barbara Jonchère, Anand Mayasundari, Aaron Pitre, Jennifer Hadley, Leena Paul, Melissa Batts, Brandon Bianski, Christopher L. Tinkle, Brent A. Orr, Zoran Ranković, Giles Robinson, Martine F. Roussel, Brandon J. Wainwright, Lena M Kutscher, Hong Lin, Paul A. Northcott   +21 more
openalex   +1 more source

ZmELP1, an Elongator complex subunit, is required for the maintenance of histone acetylation and RNA Pol II phosphorylation in maize kernels

Plant Biotechnology Journal, Volume 22, Issue 5, Page 1251-1268, May 2024.
Summary The Elongator complex was originally identified as an interactor of hyperphosphorylated RNA polymerase II (RNAPII) in yeast and has histone acetyltransferase (HAT) activity. However, the genome‐wide regulatory roles of Elongator on transcriptional elongation and histone acetylation remain unclear. We characterized a maize miniature seed mutant,
Jianrui Li, Wei Gu, Zhijia Yang, Jian Chen, Fei Yi, Tong Li, Jingrui Li, Yue Zhou, Yan Guo, Weibin Song, Jinsheng Lai, Haiming Zhao   +11 more
wiley   +1 more source

Les cacaoyers spontanés de Guyane. Nouvelles prospections [PDF]

, 1997
L'article relate de nouvelles prospections de cacaoyers spontanés, en 1995, dans le sud-est de la Guyane française. Deux nouvelles zones ont été étudiées, les berges des rivières Euleupousing et Yaloupi, affluents du haut-Oyapok, et quelques prélèvements
Couturier, Christophe, Lachenaud, Philippe, Mooleedhar, Vishnarayan   +2 more
core  

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source