Results 91 to 100 of about 1,253 (161)

The familial dysautonomia disease gene IKBKAP is required in the developing and adult mouse central nervous system

Disease Models & Mechanisms, 2017
Hereditary sensory and autonomic neuropathies (HSANs) are a genetically and clinically diverse group of disorders defined by peripheral nervous system (PNS) dysfunction.
Marta Chaverra, Lynn George, Marc Mergy, Hannah Waller, Katharine Kujawa, Connor Murnion, Ezekiel Sharples, Julian Thorne, Nathaniel Podgajny, Andrea Grindeland, Yumi Ueki, Steven Eiger, Cassie Cusick, A. Michael Babcock, George A. Carlson, Frances Lefcort   +15 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Tumor Reduction, Delayed Neurological Deficits, and Extended Survival by Thermal Targeting of Bac-ELP1-H1. A.

, 2013
Representative MRI images of rats from each treatment group. The arrows point to the tumors’ location. ** Animal didn’t survive to the final scan. B. Series of axial sections from a representative animal from saline (top), saline+hyperthermia (middle ...
Gene L. Bidwell III (277232), Majid Khan (277235), Eddie Perkins (277233), Drazen Raucher (277237), Joshua Hughes (277234), Judy R. James (277236)   +5 more
core   +1 more source

Gene expression analysis of the biocontrol fungus Trichoderma harzianum in the presence of tomato plants, chitin, or glucose using a high-density oligonucleotide microarray

BMC Microbiology, 2009
Background It has recently been shown that the Trichoderma fungal species used for biocontrol of plant diseases are capable of interacting with plant roots directly, behaving as symbiotic microorganisms.
Suárez M Belén, Vizcaíno Juan, Monte Enrique, de Luis Alberto, Samolski Ilanit   +4 more
doaj   +1 more source

Supplemental_Material_for_Devel_Screen_Platf_to_ident_small_molecules_modyf_splicing_in_FD_by_Salani_et_al – Supplemental material for Development of a Screening Platform to Identify Small Molecules That Modify ELP1 Pre-mRNA Splicing in Familial Dysautonomia

, 2018
Supplemental material, Supplemental_Material_for_Devel_Screen_Platf_to_ident_small_molecules_modyf_splicing_in_FD_by_Salani_et_al for Development of a Screening Platform to Identify Small Molecules That Modify ELP1 Pre-mRNA Splicing in Familial ...
Ranjit Shetty (5613053), Fabio Urbina (5613044), Susan A. Slaugenhaupt (5613071), Emily A. Law (5613059), Graham Johnson (1336800), Lisa Minor (5613068), Monica Salani (5613041), C. Scott Gallagher (5613056), Dylan J. Finneran (5613065), Anthony Brenner (5613047), Elisabetta Morini (5613050), Sara Sunshine (5613062)   +11 more
core   +1 more source

Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model

Metabolites
Neurodegenerative retinal diseases such as glaucoma, diabetic retinopathy, Leber’s hereditary optic neuropathy (LHON), and dominant optic atrophy (DOA) are marked by progressive death of retinal ganglion cells (RGC).
Stephanann M. Costello, Anastasia Schultz, Donald Smith, Danielle Horan, Martha Chaverra, Brian Tripet, Lynn George, Brian Bothner, Frances Lefcort, Valérie Copié   +9 more
doaj   +1 more source

Plasma Pharmacokinetics of Each CPP-ELP^a.

, 2013
aPlasma clearance data following IV injection of rhodamine-labeled ELP1, SynB1-ELP1, or Bac-ELP1 were fit to a two compartment pharmacokinetic model.
Gene L. Bidwell III (277232), Majid Khan (277235), Eddie Perkins (277233), Drazen Raucher (277237), Joshua Hughes (277234), Judy R. James (277236)   +5 more
core   +1 more source

Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4

, 2009
P>In yeast, the role for the Elongator complex in tRNA anticodon modification is affected by phosphorylation of Elongator subunit Elp1. Thus, hyperphosphorylation of Elp1 due to inactivation of protein phosphatase Sit4 correlates with Elongator-minus ...
Raffael Schaffrath, Constance Mehlgarten, Jablonowski, Daniel, Mehlgarten, Constance, Stark, Michael J. R., Breunig, Karin D., Daniel Jablonowski, Karin D. Breunig, Schaffrath, Raffael, Michael J. R. Stark   +9 more
core   +1 more source

Biodistribution of CPP-ELPs Following IV Injection.

, 2013
Organ distribution of rhodamine-labeled ELP1, SynB1-ELP1, or Bac-ELP1 was determined 4 h after IV administration by quantitative fluorescence analysis. Bars, s.e.
Gene L. Bidwell III (277232), Majid Khan (277235), Eddie Perkins (277233), Drazen Raucher (277237), Joshua Hughes (277234), Judy R. James (277236)   +5 more
core   +1 more source

Medulloblastomas with ELP1 pathogenic variants: A weakly penetrant syndrome with a restricted spectrum in a limited age window

Neuro-Oncology Advances
Abstract Background ELP1 pathogenic variants (PV) have been recently identified as the most frequent variants predisposing to Sonic Hedgehog (SHH) medulloblastomas (MB); however, guidelines are still lacking for genetic counseling in this new syndrome.
Léa Guerrini-Rousseau, Julien Masliah-Planchon, Mathilde Filser, Arnault Tauziède-Espariat, Natacha Entz-Werle, Christine M Maugard, Saskia M J Hopman, Jacob Torrejon, Marion Gauthier-Villars, Fatoumata Simaga, Thomas Blauwblomme, Kevin Beccaria, Etienne Rouleau, Marina Dimaria, Jacques Grill, Samuel Abbou, Béatrice Claret, Laurence Brugières, François Doz, Yassine Bouchoucha, Cécile Faure-Conter, Valerie Bonadona, Ludovic Mansuy, Emilie de Carli, Olivier Ingster, Clémentine Legrand, Anne Pagnier, Pascaline Berthet, Damien Bodet, Sophie Julia, Anne-Isabelle Bertozzi, Marjolaine Wilems, Claude-Alain Maurage, Olivier Delattre, Olivier Ayrault, Christelle Dufour, Franck Bourdeaut   +36 more
openaire   +3 more sources