Results 71 to 80 of about 1,253 (161)

External validation of and improvement upon a model for the prediction of placenta accreta spectrum severity using prospectively collected multicenter ultrasound data

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 104, Issue S1, Page 20-28, April 2025.
This study evaluated the Sargent risk stratification algorithm for predicting placenta accreta spectrum (PAS) severity across multiple centers using the IS‐PAS database. The algorithm's ability to differentiate between abnormally adherent (FIGO grade 1) and invasive placenta (FIGO grades 2 and 3) was assessed, and a new model was developed based on ...
Magdalena Kolak   +27 more
wiley   +1 more source

Modelling neurocardiac physiology and diseases using human pluripotent stem cells: current progress and future prospects

open access: yesThe Journal of Physiology, Volume 603, Issue 7, Page 1865-1885, 31 March 2025.
Abstract figure legend Summary of strategies in modelling neurocardiac interactions using human pluripotent stem cells. Abstract Throughout our lifetime the heart executes cycles of contraction and relaxation to meet the body's ever‐changing metabolic needs. This vital function is continuously regulated by the autonomic nervous system.
Hsueh‐Fu Wu   +4 more
wiley   +1 more source

The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.

open access: yesPLoS Genetics, 2010
Although acetylated alpha-tubulin is known to be a marker of stable microtubules in neurons, precise factors that regulate alpha-tubulin acetylation are, to date, largely unknown.
Jachen A Solinger   +9 more
doaj   +1 more source

Assessment of genetically modified maize DAS1131 (application GMFF‐2021‐1530)

open access: yesEFSA Journal, Volume 23, Issue 3, March 2025.
Abstract Genetically modified maize DAS1131 was developed to confer resistance to certain susceptible lepidopteran pests, as well as tolerance to glyphosate herbicide, these properties were achieved by introducing the cry1Da2 and dgt‐28 epsps expression cassettes.
EFSA Panel on Genetically Modified Organisms (GMO)   +31 more
wiley   +1 more source

TMOD-19. GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA

open access: yes
Germline loss-of-function (LOF) variants in Elongator complex protein 1 (ELP1) are the most prevalent predisposing genetic events observed in medulloblastoma (MB), accounting for 30% of the Sonic Hedgehog 3 subtype (SHH-3).
Soliman, Taha   +31 more
core   +1 more source

Methyl Viologen as a Redox Mediator for Scanning Electrochemical Microscopy to Study Copper Corrosion Under Deaerated Conditions

open access: yesElectroanalysis, Volume 37, Issue 2, February 2025.
Exploring methyl viologen as a redox mediator for probing corroding copper via scanning electrochemical microscopy, this study highlights its effectiveness under anoxic conditions for accurate corrosion analysis. The work underscores the importance of mediator selection and need to prevent interference from species like oxygen. Scanning electrochemical
Emmanuel Mena‐Morcillo   +4 more
wiley   +1 more source

MDB-13. GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA

open access: yes
BACKGROUND Germline loss-of-function (LOF) variants in Elongator complex protein 1 (ELP1) are the most prevalent predisposing genetic events observed in medulloblastoma (MB), accounting for 30% of the Sonic Hedgehog 3 subtype (SHH-3).
Soliman, Taha   +30 more
core   +1 more source

ALP1 and ELP1 – novel genetic modifiers of LIKE HETEROCHROMATIN PROTEIN 1 participate in Polycomb mediated gene repression in Arabidopsis [PDF]

open access: yes, 2012
Polycomb Group (PcG) proteins are involved in the inheritance of phenotypic traits by repressing the expression of target genes through binding of chromatin. In Arabidopsis thaliana several Polycomb Repressive Complexes (PRCs) are active during different
Hartwig, B., Hartwig, Benjamin
core   +1 more source

Fronto‐Parietal and Language Network Connectivity and Its Association With Gene Expression Profiles in Bipolar Disorder Before and After Treatment

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
Increased functional activity of the fronto‐parietal network (FPN) and language network (LN) might be involved in the pathogenetic mechanisms of bipolar disorder (BD). After treatment, baseline FCs were partially normalized, highlighting potential therapeutic mechanisms.
Leyi Zhang   +9 more
wiley   +1 more source

In vitro phosphorylation of peptides corresponding to the Elp1 C-terminal region by Hrr25.

open access: yes, 2015
(A) Sequences of synthetic peptides used as substrates shown in alignment with Elp1 residues 1191-1230. Lower-case bold letters represent alanine and/or glutamate substitutions relative to the native Elp1 sequence.
Wael Abdel-Fattah (682306)   +9 more
core   +1 more source

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