Results 31 to 40 of about 1,780 (194)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

El consenso a la imposición en la fiscalidad global

Thēmis, 2019
El ámbito económico internacional de las naciones ha sufrido cambios acelerados desde el final del siglo XX hasta nuestros días. El aislacionismo económico característico de siglos anteriores al nuestro ha quedado en el pasado y, así, las instituciones ...
Francesco Farri
doaj  

Experticia, vaguedad y máximas de la experiencia en los casos de elusión fiscal

Derecho PUCP
El objetivo principal de esta investigación es analizar la vaguedad como un problema probatorio en casos de elusión fiscal, evaluando su impacto en la capacidad del órgano juzgador para determinar si los hechos específicos de un caso pueden ser ...
Hugo Osorio Morales, Patricia Toledo Zúñiga   +1 more
doaj   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

CLÁUSULA ANTIABUSO VERSUS FRAUDE DE LEY: ¿DOS CONCEPTOS SEMEJANTES EN LA LEY GENERAL TRIBUTARIA? [PDF]

Crónica Tributaria, 2007
El presente trabajo pretende analizar el alcance y la naturaleza que ofrece la figura de la «cláusula antiabuso» o «conflicto en la aplicación de la norma» en la Ley 58/2003, de 17 de diciembre, General Tributaria, a través de un estudio comparativo de ...
Juan Calvo Vérgez
doaj  

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Procedimiento para aplicar la cláusula general antiabuso

Revista de Derecho Fiscal, 2017
Por décadas Colombia ha tenido una gran preocupación por el riesgo de la elusión fiscal, por esta razón el Congreso colombiano introdujo en su estatuto fiscal la Norma General Antielusión, mediante la Ley 1607 de 2012.
Pablo Mauricio Sarmiento Mancipe
doaj   +1 more source

Extremely Long Electron Lifetime in Spontaneously Passivated Polycrystalline Perovskite Layers via Illumination‐Assisted Trap Filling

Advanced Functional Materials, EarlyView.
ABSTRACT Perovskite solar cells (PSCs) are promising next‐generation photovoltaics. The high performance of PSCs is attributed to the long carrier lifetimes of perovskite photoabsorbers. However, the carrier lifetimes of polycrystalline perovskite layers, which serve as the photoabsorbers in practical PSCs, have remained limited to several tens of ...
Naoyuki Nishimura, Ryuzi Katoh, Takurou N. Murakami   +2 more
wiley   +1 more source

Strong Lead‐Free Bioinspired Piezoceramics for Durable Energy Transducers

Advanced Functional Materials, EarlyView.
We fabricated brick‐and‐mortar lead‐free piezoceramics with Bi0.5Na0.5TiO3 monocrystal platelets as bricks and amorphous silica as mortar. The alignment of the bricks and the presence of the amorphous silica led to anisotropic residual stresses. These residual stresses increase the samples toughness, strength and durability while the brick alignment ...
Ruxue Yang, Temesgen Tadeyos Zate, Peiren Wang, Soumyajit Mojumder, Elo Overgaard Mogensen, Oriol Gavalda‐Diaz, Zihe Li, Shitong Zhou, Ajeet Kumar, James Roscow, Hamideh Khanbareh, Astri Bjørnetun Haugen, Florian Bouville   +12 more
wiley   +1 more source

Aislamiento, patogenicidad y estudio de algunas propiedades biológicas de una cepa del virus de la enfermedad de Newcastle

Revista Científica, 2010
El presente estudio se realizó con la finalidad de evaluar la patogenicidad y algunas propiedades biológicas de una cepa del virus de la Enfermedad de Newcastle aislado de un lote de pollos de engorde.
Carmen de Noguera, Antonio León, Dilia Infante, Morella de Rolo, Roel Sánchez, Antonio Herrera   +5 more
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