Results 71 to 80 of about 274,782 (226)
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
, 2015 Los paraísos fiscales tienen sus orígenes a mediados del siglo XX, cuando países con escasos recursos atraían inversiones extranjeras a través de legislación flexible y permisiva en materia financiera y tributaria.
Bafumo, Fernando David +4 more
core
Los grupos de interés y sus efectos sobre las políticas públicas: El caso del FUT [PDF]
, 2017 Interest groups form a kind of collective action that has been widely studied in recent years due to their influence on public policy. In Chile its influence was demonstrated during the negotiation of tax reform by the government of New Majority. In this
Ruiz, Mónica
core +2 more sources
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Los aportes parafiscales y los programas de asistencia social [PDF]
, 2013 Es necesario insistir en el compromiso del Gobierno por promover incentivar la inversión y al inversionista en el territorio nacional, pero también en la convicción de defender los programas sociales que se financian con recursos provenientes de aportes
Grosso Parra, Liliana Yaneth
core
Advanced Science, EarlyView.A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng +16 more
wiley +1 more source
TASA IMPOSITIVA ÚNICA Y CUMPLIMIENTO FISCAL
El Trimestre Económico, 2012 El sistema impositivo que combina una única tasa impositiva con un mínimo exento ha sido objeto de largo debate en los años recientes. Sus detractores argumentan que los sistemas impositivos de estas características son menos progresivos y en ...
Judith Panadés
doaj
El plan de acción BEPS de la OCDE: pasado, presente y futuro [PDF]
, 2015 Este trabajo ofrece una visión general del denominado Plan de Acción BEPS de la OCDE. El estudio se divide en tres grandes bloques. En primer lugar se explica el origen del proyecto haciendo referencia a informes previos de Organizaciones Internacionales
Pedrosa López, José Carlos
core
Advanced Science, EarlyView.The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci +13 more
wiley +1 more source
Advanced Science, EarlyView.This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source