Results 91 to 100 of about 635,014 (389)

Elution of Artificial Sputum from Swab by Rotating Magnetic Field-Induced Mechanical Impingement

Applied Sciences, 2017
Cotton-tipped applicator swabs are used as a collection device for many biological samples and its complete elution is a desired step for clinical and forensic diagnostics.
Shubham Banik, James Mahony, P. Ravi Selvaganapathy   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Improved elution conditions for native co-immunoprecipitation. [PDF]

PLoS ONE, 2011
Native immunoprecipitation followed by protein A-mediated recovery of the immuno-complex is a powerful tool to study protein-protein interactions. A limitation of this technique is the concomitant recovery of large amounts of immunoglobulin, which ...
Robin Antrobus, Georg H H Borner
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Aspects of the quantitative separation and estimation of thiamine and its phosphate esters : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1981
Methods for the separation and estimation of thiamine, thiamine monophosphate and thiamine diphosphate which would be applicable to biological extracts were investigated.
Scott, Paul Noel
core  

Combination of modified mixing technique and low frequency ultrasound to control the elution profile of vancomycin-loaded acrylic bone cement

Bone & Joint Research, 2016
Objectives The objective of this study was to determine if combining variations in mixing technique of antibiotic-impregnated polymethylmethacrylate (PMMA) cement with low frequency ultrasound (LFUS) improves antibiotic elution during the initial high ...
A. Wendling, D. Mar, N. Wischmeier, D. Anderson, T. McIff   +4 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

“Block D” Phenomenon in Hemolytic Disease of Fetus and Newborn: The Immunohematological Implications

Global Journal of Transfusion Medicine
Background and Objectives: “Block D” in hemolytic disease of the fetus and newborn (HDFN) is quite rare and should be evaluated meticulously. We analyzed “Block D” phenomenon in neonates with HDFN due to rhesus (Rh) incompatibilities.
Sourav Mukherjee, Sudipta Sekhar Das, Sourav Chowdhury   +2 more
doaj   +1 more source

A simple method for non-denaturing purification of biotin-tagged proteins through competitive elution with free biotin

BioTechniques, 2020
The use of avidin or streptavidin in the purification of biotinylated proteins has been highly restricted due to the harsh and denaturing elution conditions.
Kui Lin, Qin Yan, Audrey Mitchell, Natasha Funk, Catherlin Lu, Hao Xiao   +5 more
doaj   +1 more source

Synthesis of polyformals [PDF]

, 1981
Formals of CH2OH(CHOH) sub n CH2OH polyols (n = 2 to 4) are prepared in less than 15 minutes by heating to about 125 C, a mixture of e.g. sorbitol and paraformaldehyde in slight excess (5 to 10%), in the presence of e.g.
Poshkus, A. C.
core   +1 more source