Results 91 to 100 of about 548,250 (354)

Drug-eluting stent in diabetes [PDF]

Sao Paulo Medical Journal, 2007
Long-term evaluation of cardiovascular risk among diabetic patients has shown that the incidence of death due to myocardial infarction among these patients is 20%, whereas among nondiabetic patients it is only 3.5%. Such observations haveled to classifying diabetes as a risk that is equivalent to establi shed coronary artery disease.
Walter J. Gomes, Álvaro Nagib Atallah, Álvaro Nagib Atallah, Hernani Pinto de Lemos Júnior, Hernani Pinto de Lemos Júnior   +4 more
openaire   +4 more sources

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

Molecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef, Hana Barhom, Sumit Chatterji, Netta Hecht, Oran Warhaftig, Iris Kamer, Oranit Zadok, Jair Bar, Limor Broday, Amir Onn, Michael Peled   +10 more
wiley   +1 more source

Highlighting the effects of co‐eluting interferences on compound specific stable isotope analysis of polycyclic aromatic hydrocarbons using comprehensive two‐dimensional gas chromatography [PDF]

, 2014
Accuracy is the most important issue when carrying out compound specific stable isotope analysis of polycyclic aromatic hydrocarbons extracted from complex samples.
Blessing, Buczyńska, Elsner, Gauchotte-Lindsay, Graham, Liu, Mansuy, Mazeas, McGregor, McGregor, McRae, Meier-Augenstein, Pashin, Philp, Philp, Saber, Steinbach   +16 more
core   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Interaction of the Streptomyces Wbl protein WhiD with the principal sigma factor σHrdB depends on the WhiD [4Fe-4S] cluster [PDF]

, 2020
The bacterial protein WhiD belongs to the Wbl family of iron–sulfur [Fe-S] proteins present only in the actinomycetes. In Streptomyces coelicolor, it is required for the late stages of sporulation, but precisely how it functions is unknown.
Bush, Matthew, Buttner, Mark, Crack, Jason, Le Brun, Nick, Stewart, Melissa   +4 more
core   +1 more source

“Block D” Phenomenon in Hemolytic Disease of Fetus and Newborn: The Immunohematological Implications

Global Journal of Transfusion Medicine
Background and Objectives: “Block D” in hemolytic disease of the fetus and newborn (HDFN) is quite rare and should be evaluated meticulously. We analyzed “Block D” phenomenon in neonates with HDFN due to rhesus (Rh) incompatibilities.
Sourav Mukherjee, Sudipta Sekhar Das, Sourav Chowdhury   +2 more
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Improved Native Isolation of Endogenous Protein A-Tagged Protein Complexes

BioTechniques, 2013
Here we report a modified peptide reagent useful for the rapid, native elution of protein complexes containing a Protein-A-tagged component. We tested this reagent for the elution of tagged endogenous protein complexes from yeast (Nup53p/Nup170p dimer ...
John LaCava, Nagarajan Chandramouli, Hua Jiang, Michael P. Rout   +3 more
doaj   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Evaluation of ion exchange processes in drug-eluting embolization beads by use of an improved flow-through elution method. [PDF]

, 2016
n improved method for evaluating drug release behaviour of drug-eluting embolization beads (DEBs) was developed utilizing an open-loop flow-through system, in which the beads were packed into an occlusive mass within the system and extracted with a ...
Aliberti, Amyot, Anand, Anand, Andhariya, Andrew L. Lewis, Biondi, Brown, Butler, Cheung, Cremers, D'Souza, Degenhardt, Fiorentini, Fotaki, Glen, Gonzalez, Groth, Harland, Helfferich, Jasmine John, Jordan, Kakhi, Laura J. Waters, Lewis, Lewis, Liapi, Liu, Malagari, Martin, Martin, Namur, Nicolini, Pedro Garcia, Sree Lakshmi, Tanya Swaine, Taylor, Upkar Bhardwaj, Vogl, Willmott, Wähling, Yiqing Tang, Zolnik   +42 more
core   +1 more source