Results 131 to 140 of about 637,249 (369)

Removal of antibodies from red cells: Comparison of three elution methods

Asian Journal of Transfusion Science, 2013
Background: Direct antiglobulin test (DAT) is the most common test done in immunohematology lab, which detects immunoglobulin and fragments of complement attached to the red blood cells. These coated red blood cells are difficult to accurately phenotype,
Rahul Katharia, Rajendra K Chaudhary
doaj   +1 more source

Optimization of pressurized liquid extraction using a multivariate chemometric approach and comparison of solid phase extraction cleanup steps for the determination of polycyclic aromatic hydrocarbons in mosses [PDF]

, 2012
A factorial design was used to optimize the extraction of polycyclic aromatic hydrocarbons (PAHs) from mosses, plants used as biomonitors of air pollution.
Foan, Louise, Simon, Valérie
core   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A Suppression Method for Elution of F−, [B(OH)4]−, AsO43−, and CrO42− from Industrial Wastes Using Some Inhibitors and Crushed Stone Powder

Technologies, 2018
The disposal and the reuse of industrial wastes have become increasingly difficult due to the elution of hazardous anions, such as F−, [B(OH)4]−, AsO43−, and CrO42−.
Xiaoxu Kuang, Atsuki Sentoku, Atsushi Sasaki, Masatoshi Endo   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

In vitro Study of Elution Characteristics of Antiviral Drugs Immersed in Bone Cement

Туберкулез и болезни лёгких
The objective: to assess elution characteristics of certain antiviral drugs immersed in bone cement samples and placed in a liquid medium to determine the fundamental possibility of using such systems.Subjects and Methods.
E. O. Peretsmanas, A. A. Artyukhov, I. A. Gerasimov, V. S. Zubikov, T. E. Tyulkova, Ya. A. Rukin   +5 more
doaj   +1 more source

Expression and purification of an NSD3-GB1 fusion protein as a way to study the structure of complex formation with Brd4 ET. [PDF]

, 2020
The BRD4 protein belongs to the bromodomain and extraterminal domain (BET) family of eukaryotic transcription factors, and is linked to several types of cancer, inflammation, and obesity.
Tuokkola, Jennifer
core  

Nanoporous Titanium Surfaces for Sustained Elution of Proteins and Antibiotics

PLoS ONE, 2014
Current medically relevant metals for prosthetic reconstructions enjoy a relatively good success rate, but their performance drops significantly in patients with compromised health status, and post-surgical infections still remain an important challenge.
A. Ketabchi, Kristopher Komm, Malaika Miles-Rossouw, D. Cassani, F. Variola   +4 more
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Enhancing therapeutic antibody production through amino acid-induced pH shift in Protein A affinity chromatography

Frontiers in Bioengineering and Biotechnology
Protein aggregation, denaturation, and loss of potency often occur during Protein A chromatography due to the harsh acidic conditions required for antibody elution.
Senzhu Lin, Yue Wang
doaj   +1 more source