Results 11 to 20 of about 298,245 (212)
Journal of Cardiovascular Translational Research, 2009 Coronary stenting is routinely utilized to treat symptomatic obstructive coronary artery disease. However, the efficacy of bare metal coronary stents has been historically limited by restenosis, which is primarily due to excessive neointima formation. Drug-eluting stents (DES) are composed of a stainless steel backbone encompassed by a polymer in which
Ryu, Sung Kee +2 more
openaire +5 more sources
Comparison of Zotarolimus-Eluting and Everolimus-Eluting Coronary Stents [PDF]
New England Journal of Medicine, 2010 New-generation coronary stents that release zotarolimus or everolimus have been shown to reduce the risk of restenosis. However, it is unclear whether there are differences in efficacy and safety between the two types of stents on the basis of prospectively adjudicated end points endorsed by the Food and Drug Administration.In this multicenter ...
P. W. Serruys +24 more
openaire +4 more sources
To elute or not to elute in immunocapture bottom-up LC–MS [PDF]
Journal of Chromatography B, 2017 Immunocapture-based bottom-up LC-MS is a promising technique for the quantification of low abundant proteins. Magnetic immunocapture beads provide efficient enrichment from complex samples through the highly specific interaction between the target protein and its antibody.
Levernæs, Maren Christin Stillesby +3 more
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Everolimus-eluting versus paclitaxel-eluting stents
The Lancet, 2010 Lancet
Kounis, N. G., Goudevenos, J. A.
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BMJ, 2006 Last week an expert panel of the US Food and Drug Administration (FDA) recommended that the FDA should issue warnings to doctors and patients about drug eluting coronary stents. The safety of such stents is unclear except in low risk patients. Furthermore, patients with drug eluting stents should take antiplatelet therapy for at least one year after ...
Gershlick, AH, Richardson, G
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Paclitaxel-Eluting Balloons for Sirolimus-Eluting Stent Restenosis
JACC: Cardiovascular Interventions, 2011 We read with interest the randomized study by Habara et al. ([1][1]) comparing paclitaxel-eluting balloon (PB) (n = 25) with conventional balloon (BA) (n = 25) in patients suffering from sirolimus-eluting stent (SES) in-stent restenosis (ISR).
Manuel Paulo +3 more
openaire +3 more sources
Canadian Medical Association Journal, 2007 In their recent systematic review, Suzanne Ligthart and associates compared analyses of the cost-effectiveness of drug-eluting stents.[1][1] They found that in most studies in which an incremental cost-effectiveness ratio greater than $50 000 per quality-adjusted life-year was calculated the ...
Tangri N, Falcone El
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A meta-analysis of everolimus-eluting stents versus sirolimus-eluting stents and paclitaxel-eluting stents in diabetic patients [PDF]
Journal of Cardiothoracic Surgery, 2021 Abstract Objective We performed this meta-analysis to determine which stent among everolimus eluting stents (EES), sirolimus eluting stents (SES) and paclitaxel eluting stents (PES) should be preferred for the treatment of DM patients.
Zheng Tao +8 more
openaire +3 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source