Pathogenesis of Aleutian Disease of Mink: Nature of the Antiglobulin Reaction and Elution of Antibody from Erythrocytes and Glomeruli of Infected Mink [PDF]
, 1973 Ha-eun Cho, D. G. Ingram
openalex +1 more source
Advanced Healthcare Materials, EarlyView.AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan +3 more
wiley +1 more source
Tuning hydrogen bonds and electrostatics with convection for purifying mRNA: A paradigm shift. [PDF]
Sci AdvNeuman TG +7 more
europepmc +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
A Novel Protein Purification Approach Using Elastin-Like Polypeptides (ELP) With His-Tag Assistance. [PDF]
Bio ProtocChae YK, Shin HB.
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General ligands and (Co)substrate elution in affinity chromatography [PDF]
, 1972 Klaus Mosbach +3 more
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Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
Advanced Healthcare Materials, EarlyView.This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla +16 more
wiley +1 more source
From Retention Time to Functional Group Assignment: A Chemical Database-Driven Approach for High-Resolution Mass Data of Marine Dissolved Organic Matter. [PDF]
Rapid Commun Mass SpectromMoye F +4 more
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Comparison of the Fractionation Efficiencies of Elution Method and Precipitation Chromatography of Polymer Fractionation [PDF]
, 1972 Minoru Ueda
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Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
Advanced Healthcare Materials, EarlyView.This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis +6 more
wiley +1 more source