Results 71 to 80 of about 635,014 (389)

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

CONDUTIVIDADE HIDRÁULICA NO PROCESSO DE ELUIÇÃO EM UM SOLO BRUNO-NÃO-CÁLCICO

open access: yesScientia Agricola, 1996
Com o objetivo de avaliar o efeito da porcentagem de sódio trocável do solo e da concentração eletrolítica da água de percolação, sobre a condutividade hidráulica em um solo Bruno-Não-Cálcico da região do Rio Salitre-BA, o presente experimento foi ...
L.N.V. DE ANDRADE, D.E CRUCIANI
doaj   +1 more source

Obtaining a bioadsorbent from orange peel suitable for batch and continous treatment [PDF]

open access: yes, 2020
One form of chemical contamination involves the contribution of heavy metals to the ecosystem mainly from industrial spills and mining operations. The most toxic heavy metals are cadmium, copper, chromium, mercury, nickel, lead and zinc.
García Raurich, Josep   +2 more
core   +3 more sources

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Impact of Manual Addition of Vancomycin to Polymethylmethacrylate (PMMA) Cements

open access: yesAntibiotics
(1) Background: The addition of antibiotics to bone cements is a common practice in the treatment of periprosthetic joint infections. In revision cases, the amount and type of antibiotic is often insufficient and additional antibiotics must be added. The
Clemens Kittinger   +2 more
doaj   +1 more source

Microscale Rearrangement of Ammonium Induced by Snow Metamorphism

open access: yesFrontiers in Earth Science, 2019
Earth’s snowpack hosts chemical impurities that exchange with the overlying air, strongly impacting atmospheric chemistry. Being embedded in firn and glacier ice formed from surface snow, impurities provide the basis for reconstructing past atmospheric ...
Jürg C. Trachsel   +11 more
doaj   +1 more source

"Dry-column" chromatography of plant pigments [PDF]

open access: yes, 1973
Separation of plant pigments which can be accomplished on thin-layer silica plates with mixture of petroleum ether, halocarbon, acetone, and polar solvent can be readily translated into dry-column technique that yields reproducible chromatograms after ...
Lehwalt, M. F.   +2 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

SEC-MALS characterization of natural rubber: Study of phenomena behind the abnormal elution profile [PDF]

open access: yes, 2008
Natura/ and synthetic poly(cis-1,4-isoprene) were characterized by size exclusion chromatography coupled with an online multiangle light scattering detector (SEC-MALS) (Fig. 1).
Kim, Chandy   +4 more
core  

Sulfanilic acid-modified chitosan mini-spheres and their application for lysozyme purification from egg white [PDF]

open access: yes, 2018
A cation exchange matrix with zwitterionic and multimodal properties was synthesized by a simple reaction sequence coupling sulfanilic acid to a chitosan based support. The novel chromatographic matrix was physico-chemically characterized by ss-NMR and ζ
Baieli, María Fernanda   +7 more
core   +1 more source

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