Results 71 to 80 of about 637,249 (369)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
amsrpm: Robust Point Matching for Retention Time Aligment of LC/MS Data with R
Journal of Statistical Software, 2007 Proteomics is the study of the abundance, function and dynamics of all proteins present in a living organism, and mass spectrometry (MS) has become its most important tool due to its unmatched sensitivity, resolution and potential for high-throughput ...
Marc Kirchner +4 more
doaj
SEC-MALS characterization of natural rubber: Study of phenomena behind the abnormal elution profile [PDF]
, 2008 Natura/ and synthetic poly(cis-1,4-isoprene) were characterized by size exclusion chromatography coupled with an online multiangle light scattering detector (SEC-MALS) (Fig. 1).
Kim, Chandy +4 more
core
Two-phase wash to solve the ubiquitous contaminant-carryover problem in commercial nucleic-acid extraction kits [PDF]
, 2020 The success of fundamental and applied nucleic acid (NA) research depends on NA purity, but obtaining pure NAs from raw, unprocessed samples is challenging.
Ismagilov, Rustem F. +2 more
core
Chemical analysis of soluble fractions from normal and autolysed rabbit liver by column chromatography [PDF]
, 1966 Chromatography on Sephadex G-200 was performed with the soluble fraction of homogenated rabbit liver, which was extracted with 0.1 M phosphate buffer containing 0.1 M NaCl.
Aizawa, Tadashi +4 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Complete gradient-LC-ESI system on a chip for protein analysis [PDF]
, 2005 This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed ...
Lee, T. D. +3 more
core
Paclitaxel-Eluting Balloons for Sirolimus-Eluting Stent Restenosis
JACC: Cardiovascular Interventions, 2011 We read with interest the randomized study by Habara et al. ([1][1]) comparing paclitaxel-eluting balloon (PB) (n = 25) with conventional balloon (BA) (n = 25) in patients suffering from sirolimus-eluting stent (SES) in-stent restenosis (ISR).
Alfonso, Fernando +3 more
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Asian Journal of Transfusion ScienceBlood group discrepancies and their resolution can sometimes become tricky when it comes to weaker subgroups. A number of weaker B subgroups, which are very infrequently encountered, have been described, including B3, Bx, Bm, and Bel.
Vaidehi Prasanth +7 more
doaj +1 more source