Cefepime exposure in prolonged or intermittent infusion in critically ill children
British Journal of Clinical Pharmacology, EarlyView.Aims Cefepime is commonly used in critically ill children for whom there is a high between‐subject variability. To reach the therapeutic pharmacokinetic (PK) target in critically ill patients, prolonged infusion of beta‐lactams seems to be the most efficient.
Marc Hobeika +12 more
wiley +1 more source
Using Mobile Technology to Study Episodes of Alcohol Self-Administration in Daily Life: A Narrative Review. [PDF]
Curr Addict RepFridberg DJ +4 more
europepmc +1 more source
Medicines, misinformation and machines: Navigating infodemics in the generative AI era
British Journal of Clinical Pharmacology, EarlyView.Health information is now widely accessed through smartphones, online searches and increasingly through generative artificial intelligence (AI). These systems create new opportunities for communication, and in some routine contexts, well‐governed AI assistants could reduce exposure to lower quality sources by providing cautious, evidence‐aligned ...
Natansh D. Modi +3 more
wiley +1 more source
Associations of momentary food availability and appetitive drive with adolescents' food intake and dysregulated eating in a community sample of adolescents: The moderating role of trait hedonic hunger. [PDF]
Appl Psychol Health Well BeingLuo Y, Morales JC, Smith KE, Mason TB.
europepmc +1 more source
Biopharmaceutics &Drug Disposition, EarlyView.Pharmacokinetic interactions between Echinacea and two antiviral drugs, favipiravir and atazanavir, were assessed in rats. The findings suggest that Echinacea does not significantly affect the pharmacokinetics of favipiravir and atazanavir. These results provide preliminary evidence that concurrent use of Echinacea with these antiviral drugs may be ...
Siva Nageswara Rao Gajula +4 more
wiley +1 more source
Evaluating temporal associations between executive functioning, stress and physical activity among adolescents at risk for type 2 diabetes: protocol for an ecological momentary assessment study. [PDF]
BMJ OpenGutierrez-Colina AM +9 more
europepmc +1 more source
What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?
Biotechnology and Bioengineering, EarlyView.Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady +6 more
wiley +1 more source
Adherence and Acceptability of Smartphone- and Wearable-Based Digital Phenotyping in Patients With First-Episode Psychosis: Observance et acceptabilité du phénotypage numérique fondé sur les téléphones intelligents et les objets personnels connectés chez les patients présentant un premier épisode de psychose. [PDF]
Can J PsychiatryYang L +8 more
europepmc +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT There is a growing demand in the pharmaceutical industry to optimize analytical methodologies, reducing time and resource consumption while ensuring rapid process development and cost‐efficient manufacturing. Indeed, Food and Drug Administration (FDA) introduced the Process Analytical Technology (PAT) as an initiative enabling manufacturers to
Samuele Fiorenza +5 more
wiley +1 more source