Results 71 to 80 of about 91,140 (235)

Scientific Rationale for Waiving Clinical Efficacy Testing of Biosimilars

Drug Design, Development and Therapy, 2022
Sarfaraz Niazi Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois, Chicago, IL, USACorrespondence: Sarfaraz Niazi, Email niazi@niazi.comAbstract: After 18 years and the administration of billions of doses, there is little ...
Niazi S
doaj  

Cholangiocarcinoma in an American Rhea (Rhea Americana araneipes)

Ciência Rural, 2015
Cholangiocarcinomas are neoplasms that originate from the bile duct epithelium. The present case described a cholangiocarcinoma in an adult female American Rhea (Rhea Americana araneipes) by means of gross, histopathology and immunohistochemistry ...
Paulo Ricardo Dell'Armelina Rocha, Letícya Lerner Lopes, Laura Peixoto de Arruda, Caroline Argenta Pescador, Raquel Aparecida Sales da Cruz, Edson Moleta Colodel   +5 more
doaj   +1 more source

Integrating Artificial Intelligence With Droplet‐Based Microfluidics: Advances, Challenges, and Emerging Opportunities

Advanced Intelligent Systems, EarlyView.
Droplet‐based microfluidics enables precise, high‐throughput microscale reactions but continues to face challenges in scalability, reproducibility, and data complexity. This review examines how artificial intelligence enhances droplet generation, detection, sorting, and adaptive control and discusses emerging opportunities for clinical and industrial ...
Junyan Lai, Sukrit Gaira, Rongfeng Wang, Qingtian Zhang, Ming Li, Liao Wu, Diangeng Li, Yi Li, Chengchen Zhang, Jinhong Guo, Shi‐Yang Tang   +10 more
wiley   +1 more source

Planning Clinical Trial Programme for Bowel Cleansing Medicinal Products (Review)

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Colon cleansing plays an essential role in preparation for diagnostic procedures and surgical interventions. One of the key factors ensuring high-quality colon cleansing is the correct choice of a medicinal product that affects the ...
I. A. Proskurina, T. E. Gorskaya, R. S. Ilin, D. V. Goryachev   +3 more
doaj   +1 more source

Efeito de níveis de cálcio da dieta de filhotes de ema (Rhea americana, Linnaeus, 1758), na prevenção do encurvamento de pernas, em cativeiro

Revista Brasileira de Zootecnia, 1999
O objetivo deste trabalho foi avaliar dois níveis de cálcio (0,7 e 1,4%) na dieta de filhotes de ema (Rhea americana). Doze filhotes de ema com 30 dias de idade foram distribuídas, em pares, em seis piquetes com 100 m², em delineamento experimental ...
Marisa E. Sanchez Bastos, Helder Louvandini, Marcia Nogueira, Cristian A. Carranza, Abel Lavorenti   +4 more
doaj   +1 more source

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Translating Biomedical Research to Medical Devices: A Practical Guide and the Arteriovenous Graft Case Study

Advanced NanoBiomed Research, EarlyView.
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani, Nina Bono, Alice Caldiroli, Stefania Adele Riboldi, Gabriele Candiani   +4 more
wiley   +1 more source

Unsafe action detection algorithm of underground personnel in coal mine based on YOLOv8

Meitan kexue jishu
There are problems such as interference information, low illumination and mechanical equipment occlusion in the complex environment of underground coal mine, which makes the speed and accuracy of the existing object detection algorithm have a series of ...
Wei CHEN, Zhicheng JIANG, Zijian TIAN, Fan ZHANG, Yi LIU   +4 more
doaj   +1 more source

Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi, Saeed Vafaei‐Nezhad, Ahmad Gholamalizadeh Ahangar   +2 more
wiley   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source