Results 91 to 100 of about 7,417 (254)

Farabi Felsefesinde el-Evvel

Eskiyeni, 2016
Farabi metafiziğinde, varlıkların ilk mertebesinde, bütün mevcudatın İlk Sebeb’i olan İlk Mevcut (el Mevcudu’l-Evvel) yer almaktadır. İlk Mevcut’un hiyerarşik yapıda en üstte yer alması, bir konumlandırma olmanın ötesinde, bütün bir varlığı anlamada ve ...
Mehmet Murat Karakaya
doaj  

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Online $$^{222}$$ 222 Rn removal by cryogenic distillation in the XENON100 experiment

European Physical Journal C: Particles and Fields, 2017
We describe the purification of xenon from traces of the radioactive noble gas radon using a cryogenic distillation column. The distillation column was integrated into the gas purification loop of the XENON100 detector for online radon removal.
E. Aprile, J. Aalbers, F. Agostini, M. Alfonsi, F. D. Amaro, M. Anthony, F. Arneodo, P. Barrow, L. Baudis, B. Bauermeister, M. L. Benabderrahmane, T. Berger, P. A. Breur, A. Brown, E. Brown, S. Bruenner, G. Bruno, R. Budnik, L. Bütikofer, J. Calvén, J. M. R. Cardoso, M. Cervantes, D. Cichon, D. Coderre, A. P. Colijn, J. Conrad, J. P. Cussonneau, M. P. Decowski, P. de Perio, P. Di Gangi, A. Di Giovanni, S. Diglio, E. Duchovni, G. Eurin, J. Fei, A. D. Ferella, A. Fieguth, D. Franco, W. Fulgione, A. Gallo Rosso, M. Galloway, F. Gao, M. Garbini, C. Geis, L. W. Goetzke, L. Grandi, Z. Greene, C. Grignon, C. Hasterok, E. Hogenbirk, R. Itay, B. Kaminsky, G. Kessler, A. Kish, H. Landsman, R. F. Lang, D. Lellouch, L. Levinson, M. Le Calloch, Q. Lin, S. Lindemann, M. Lindner, J. A. M. Lopes, A. Manfredini, I. Maris, T. Marrodán Undagoitia, J. Masbou, F. V. Massoli, D. Masson, D. Mayani, Y. Meng, M. Messina, K. Micheneau, B. Miguez, A. Molinario, M. Murra, J. Naganoma, K. Ni, U. Oberlack, S. E. A. Orrigo, P. Pakarha, B. Pelssers, R. Persiani, F. Piastra, J. Pienaar, M.-C. Piro, V. Pizzella, G. Plante, N. Priel, L. Rauch, S. Reichard, C. Reuter, A. Rizzo, S. Rosendahl, N. Rupp, R. Saldanha, J. M. F. dos Santos, G. Sartorelli, M. Scheibelhut, S. Schindler, J. Schreiner, M. Schumann, L. Scotto Lavina, M. Selvi, P. Shagin, E. Shockley, M. Silva, H. Simgen, M. v. Sivers, A. Stein, D. Thers, A. Tiseni, G. Trinchero, C. Tunnell, N. Upole, H. Wang, Y. Wei, C. Weinheimer, J. Wulf, J. Ye, Y. Zhang, XENON Collaboration, I. Cristescu   +122 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

YENİ - PLATONCULUKTA İNSAN

Felsefe Dünyası, 2004
mekânını terk etmiş değildir.7 Ancak Ruh, kendisinin bu imajına ikinci kez bakar ve bu imaja hayran olarak, ontik ve etik anlamda kendisinden daha aşağıda olan bu imaja doğru atılır ...
Fulya Bayraktar
doaj  

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

The Necessity and Goodness of Animals in Sijistānī’s Kashf Al-Maḥjūb

Philosophies
The Neoplatonic notion of “emanation” implies a required progression through hierarchical stages, originating from the highest principle (the One or God) and cascading down through a series of principles.
Peter Adamson, Hanif Amin Beidokhti
doaj   +1 more source

Anomalous radon emanation linked to preseismic electromagnetic phenomena [PDF]

Natural Hazards and Earth System Sciences, 2007
Anomalous emanation of radon (²²²Rn) was observed preceding large earthquakes and is considered to be linked to preseismic electromagnetic phenomena (e.g.
Y. Omori, Y. Yasuoka, H. Nagahama, Y. Kawada, T. Ishikawa, S. Tokonami, M. Shinogi   +6 more
doaj  

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source