Results 91 to 100 of about 476,925 (295)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk   +5 more
wiley   +1 more source

Translation of Hedges in Medical Databases to Other Platforms’ Syntax May Cause Significantly Different Search Results. A Review of: Bradley, S. M. (2010). Examination of the clinical queries and systematic review “hedges” in EMBASE and MEDLINE. Journal of the Canadian Health Libraries Association, 31, 27-37.

open access: yesEvidence Based Library and Information Practice, 2011
Objective – To determine whether the methodological search filters in OvidSP MEDLINE and OvidSP EMBASE also known as Clinical Queries hedges had been modified from the originals which were written by the McMaster University Health Information Research ...
Heather Ganshorn
doaj  

Edaravone dexborneol compared to edaravone in the treatment of acute cerebral infarction: A meta-analysis

open access: yesFrontiers in Pharmacology
ObjectiveThe objective of this study was to systematically assess the clinical efficacy and safety of edaravone dexborneol compared to those of edaravone in treating acute cerebral infarction.MethodsWe searched the PubMed, Cochrane Library, Embase, CBM ...
Yanshuo Shi   +6 more
doaj   +1 more source

Beyond the happy sheets! Evaluating learning in information skills teaching [PDF]

open access: yes, 2004
This paper reviews three years of data measuring students' immediate reactions to a computer-assisted learning package in information skills and reports on work in progress to establish a more comprehensive programme of evaluation which will assess the ...
German, R.   +5 more
core   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

Identifying nurse staffing research in Medline: development and testing of empirically derived search strategies with the PubMed interface [PDF]

open access: yes, 2010
Background: The identification of health services research in databases such as PubMed/Medline is a cumbersome task. This task becomes even more difficult if the field of interest involves the use of diverse methods and data sources, as is the case with ...
Dunton, Nancy E.   +11 more
core   +2 more sources

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić   +8 more
wiley   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum   +5 more
wiley   +1 more source

Statistical Measures Alone Cannot Determine Which Database (BNI, CINAHL, MEDLINE, or EMBASE) Is the Most Useful for Searching Undergraduate Nursing Topics

open access: yesEvidence Based Library and Information Practice, 2011
A Review of: Stokes, P., Foster, A., & Urquhart, C. (2009). Beyond relevance and recall: Testing new user-centred measures of database performance. Health Information and Libraries Journal, 26(3), 220-231.
Giovanna Badia
doaj   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot   +7 more
wiley   +1 more source

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