Results 41 to 50 of about 55,940 (225)

Enhancing Driving Safety of Personal Mobility Vehicles Using On-Board Technologies

open access: yesApplied Sciences
Accidents involving electric wheelchairs are a growing concern, with users frequently encountering obstacles that lead to collisions, tipping, or loss of balance.
Eru Choi, Tuan Anh Dinh, Min Choi
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Mitigating Selection Bias in Recommendation Systems Through Sentiment Analysis and Dynamic Debiasing

open access: yesApplied Sciences
Selection bias can cause recommendation systems to over-rely on users’ historical behavior and ignore potential interests, thus reducing the diversity and accuracy of recommendations.
Fan Zhang, Wenjie Luo, Xiudan Yang
doaj   +1 more source

A reconfigurable and compact subpipelined architecture for AES encryption and decryption

open access: yesEURASIP Journal on Advances in Signal Processing, 2023
AES has been used in many applications to provide the data confidentiality. A new 32-bit reconfigurable and compact architecture for AES encryption and decryption is presented and implemented in non-BRAM FPG in this paper.
Ke Li, Hua Li, Graeme Mund
doaj   +1 more source

Ethereum Smart Contract Analysis Tools: A Systematic Review

open access: yesIEEE Access, 2022
Blockchain technology and its applications are gaining popularity day by day. It is a ground-breaking technology that allows users to communicate without the need of a trusted middleman.
Satpal Singh Kushwaha   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

State of Charge Estimation for Li-Ion Batteries: An Edge-Based Data-Driven Approach

open access: yesIEEE Access
The traditional machine learning approach requires substantial computational resources which are scarce in the embedded devices. Recently, the confluence of Edge computing with IoT has enabled resource constrained embedded devices to implement machine ...
Sesidhar Dvsr   +5 more
doaj   +1 more source

Microengineered Conductive Elastomeric Electrodes for Long-Term Electrophysiological Measurements with Consistent Impedance under Stretch

open access: yesSensors, 2015
In this research, we develop a micro-engineered conductive elastomeric electrode for measurements of human bio-potentials with the absence of conductive pastes.
Dinglong Hu   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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