Results 41 to 50 of about 51,799,739 (242)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Social SciencesThe paper departs from the observation that the role of migrant organisations (MOs) in Germany has changed significantly since the strong influx of refugees in 2015/16.
Kirsten Hoesch
doaj +1 more source
Learning Health Systems, 2023 Many health systems may host embedded researchers (ERs) and provide fiscal resources to encourage health service research. However, ERs may remain challenged to initiate research in these settings.
Matthew F. Hudson
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Advancing genomics research in Ireland. Irish Health Research Forum report and recommendations [PDF]
, 2021 This report presents the proceedings of the Irish Health Research Forum meeting on Thursday 12th November 2020 and makes key recommendations for for advancing genomics research in ...
Health Research Charities Ireland
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2013 On 15 March 2013, the Center for Embedded Systems for Critical Applications is organizing a public event to present its ongoing research projects.. The theme of the symposium is Embedded Security.
Virginia Tech. Center for Embedded Systems for Critical Applications
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2014 Dr. Haibo Zeng has joined the Bradley Department of Electrical and Computer Engineering as an assistant professor. Zeng will work with the department’s Center for Embedded Systems for Critical Applications.
Virginia Tech. Center for Embedded Systems for Critical Applications
core +1 more source
Lenke Classification of Scoliosis Based on Segmentation Network and Adaptive Shape Descriptor
Applied Sciences, 2023 Scoliosis is a common spinal deformity that seriously affects patients’ physical and mental health. An accurate Lenke classification is greatly significant for evaluating and treating scoliosis.
Dong Liu +3 more
doaj +1 more source