Results 81 to 90 of about 51,799,739 (242)
Fostering Experiential Learning and Evidence-Informed Impact in Health Systems: Reflections From a Canadian Health System Impact Fellow [PDF]
International Journal of Health Policy and ManagementFostering Experiential Learning and Evidence-Informed Impact in Health Systems: Reflections From a Canadian Health System Impact ...
Jawad Chishtie +8 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Financing the embedded value of life insurance portfolios [PDF]
In May 2004 the CFO Forum harmonized the various efforts of reporting the embedded valueof life insurance companies by issuing the European Embedded Value (EEV) Principles.In this working paper a methodology is proposed to derive a maximum lending ...
Harding, Perham +2 more
core
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Distributed Embedded Real-Time Systems - Analysis and Exploration
, 2005 This extensive and increasing use of embedded systems and their integration in everyday products mark a significant evolution in information science and technology. Nowadays embedded systems design is subject to seamless integration with the physical and
Eles, Petru Ion, +2 more
core
Irish Health Research Forum meeting. Theme: should Ireland set health research priorities? [PDF]
, 2018 This report presents the proceedings of the Irish Health Research Forum on May 21st, 2018 focusing on the topic of whether Ireland should set health research ...
Medical Research Charities Group
core
Renewal through health research: HRCI position paper 2021
, 2021 On January 28th we launched our 2021 position paper: Renewal through health research. It lays out a series of critical health research actions to help create a post-Covid Ireland where healthcare is world-class and based on evidence. It calls for:
Health Research Charities Ireland, /
core
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source