Results 91 to 100 of about 3,015,526 (334)
A central partition of molecular conformational space. II. Embedding 3D structures
, 2004 A combinatorial model of molecular conformational space that was previously developped (J. Gabarro-Arpa, Comp. Biol. and Chem. 27, (2003) 153-159), had the drawback that structures could not be properly embedded beacause it lacked explicit rotational ...
Gabarro-Arpa, Jacques
core +3 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
A multi-fragment real-time extension of projected density matrix embedding theory: Non-equilibrium electron dynamics in extended systems [PDF]
, 2022 Dariia Yehorova, Joshua S. Kretchmer
openalex +1 more source
A Class of Embedded DG Methods for Dirichlet Boundary Control of Convection Diffusion PDEs
, 2018 We investigated an hybridizable discontinuous Galerkin (HDG) method for a convection diffusion Dirichlet boundary control problem in our earlier work [SIAM J. Numer. Anal.
Chen, Gang +3 more
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Recent Advances in Energy-Efficient Routing Protocols for Wireless Sensor Networks: A Review
IEEE Access, 2016 Due to a battery constraint in wireless sensor networks (WSNs), prolonging their lifetime is important. Energy-efficient routing techniques for WSNs play a great role in doing so.
Jingjing Yan, Mengchu Zhou, Zhijun Ding
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The Gauge Integral Theory in HOL4
Journal of Applied Mathematics, 2013 The integral is one of the most important foundations for modeling dynamical systems. The gauge integral is a generalization of the Riemann integral and the Lebesgue integral and applies to a much wider class of functions. In this paper, we formalize the
Zhiping Shi +6 more
doaj +1 more source
IEEE Access, 2018 Intensity nonuniformity is one of the common issues in image segmentation, which is caused by technical limitations or external interference. In this paper, a novel region-based active contour model is presented for interleaved segmentation of images ...
Xiaoying Shan +2 more
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