Results 91 to 100 of about 2,999,661 (334)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Recent Advances in Energy-Efficient Routing Protocols for Wireless Sensor Networks: A Review
IEEE Access, 2016 Due to a battery constraint in wireless sensor networks (WSNs), prolonging their lifetime is important. Energy-efficient routing techniques for WSNs play a great role in doing so.
Jingjing Yan, Mengchu Zhou, Zhijun Ding
doaj +1 more source
Development of an Oxygen Saturation Monitoring System by Embedded Electronics [PDF]
, 2017 Measuring Oxygenation of blood (SaO2) plays a vital role in patient’s health monitoring. This is often measured by pulse oximeter, which is standard measure during anesthesia, asthma, operative and post-operative recoveries.
Venkatesan Gomathy, Manikandan
core +2 more sources
The extreme vulnerability of interdependent spatially embedded networks
, 2012 Recent studies show that in interdependent networks a very small failure in one network may lead to catastrophic consequences. Above a critical fraction of interdependent nodes, even a single node failure can invoke cascading failures that may abruptly ...
A Bashan +35 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Crypto Embedded System for Electronic Document [PDF]
, 2006 In this paper, a development of low-cost RSA-based Crypto Embedded System targeted for electronic document security is presented. The RSA algorithm is implemented in a re-configurable hardware, in this case Field Programmable Gate Array (FPGA).
Ahmad, Illiasaak +2 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The Gauge Integral Theory in HOL4
Journal of Applied Mathematics, 2013 The integral is one of the most important foundations for modeling dynamical systems. The gauge integral is a generalization of the Riemann integral and the Lebesgue integral and applies to a much wider class of functions. In this paper, we formalize the
Zhiping Shi +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
IEEE Access, 2018 Intensity nonuniformity is one of the common issues in image segmentation, which is caused by technical limitations or external interference. In this paper, a novel region-based active contour model is presented for interleaved segmentation of images ...
Xiaoying Shan +2 more
doaj +1 more source