Results 101 to 110 of about 3,015,526 (334)

Lasing in metamaterial nanostructures

open access: yes, 2009
A self-consistent computational scheme is presented for one dimensional (1D) and two dimensional (2D) metamaterial systems with gain incorporated into the nanostructures. The gain is described by a generic four-level system. The loss compensation and the
Anan Fang   +4 more
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Partial annealing of a coupled mean-field spin-glass model with an embedded pattern

open access: yes, 2010
A partially annealed mean-field spin-glass model with a locally embedded pattern is studied. The model consists of two dynamical variables, spins and interactions, that are in contact with thermal baths at temperatures T_S and T_J, respectively.
Ayaka Sakata   +4 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Optimization of Wheelchair Control via Multi-Modal Integration: Combining Webcam and EEG

open access: yesFuture Internet
Even though Electric Powered Wheelchairs (EPWs) are a useful tool for meeting the needs of people with disabilities, some disabled people find it difficult to use regular EPWs that are joystick-controlled.
Lassaad Zaway   +5 more
doaj   +1 more source

Heavy quark dynamics for charm and bottom flavor on Fermi surface at zero temperature

open access: yes, 2013
We discuss the dynamics in finite density medium including a heavy impurity particle (hadron or quark) with a heavy flavor, charm and bottom, at zero temperature.
Sudoh, K., Yasui, S.
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Development of an Oxygen Saturation Monitoring System by Embedded Electronics [PDF]

open access: yes, 2017
Measuring Oxygenation of blood (SaO2) plays a vital role in patient’s health monitoring. This is often measured by pulse oximeter, which is standard measure during anesthesia, asthma, operative and post-operative recoveries.
Venkatesan Gomathy, Manikandan
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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