Results 101 to 110 of about 1,552,847 (293)

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Architected Lattices with a Topological Transition

Advanced Engineering Materials, EarlyView., 2023
This article develops topological metamaterials showing multidirectional two‐step deformation under compression by embedding contact‐enabled topological mechanisms into lattice structures. Experiments on 3D‐printed 2D and 3D lattices and finite element simulations are conducted to demonstrate the working principle of the topological metamaterials.
Shivam Agarwal, Lihua Jin
wiley   +1 more source

Optimization of Wheelchair Control via Multi-Modal Integration: Combining Webcam and EEG

Future Internet
Even though Electric Powered Wheelchairs (EPWs) are a useful tool for meeting the needs of people with disabilities, some disabled people find it difficult to use regular EPWs that are joystick-controlled.
Lassaad Zaway, Nader Ben Amor, Jalel Ktari, Mohamed Jallouli, Larbi Chrifi Alaoui, Laurent Delahoche   +5 more
doaj   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Efficient Deep Learning Infrastructures for Embedded Computing Systems: A Comprehensive Survey and Future Envision [PDF]

arXiv
Deep neural networks (DNNs) have recently achieved impressive success across a wide range of real-world vision and language processing tasks, spanning from image classification to many other downstream vision tasks, such as object detection, tracking, and segmentation.
arxiv  

Design of Dual-Mode Local Oscillators Using CMOS Technology for Motion Detection Sensors

Sensors, 2018
Recently, studies have been actively carried out to implement motion detecting sensors by applying radar techniques. Doppler radar or frequency-modulated continuous wave (FMCW) radar are mainly used, but each type has drawbacks.
Keum-Won Ha, Jeong-Yun Lee, Jeong-Geun Kim, Donghyun Baek   +3 more
doaj   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Smart aquaculture analytics: Enhancing shrimp farming in Bangladesh through real-time IoT monitoring and predictive machine learning analysis

Heliyon
Water quality is a critical factor in shrimp farming, and the success of shrimp production is closely tied to the overall condition of the water. Challenges such as rapid population growth, environmental pollution, and global warming have led to a ...
Fizar Ahmed, Md. Hasan Imam Bijoy, Habibur Rahman Hemal, Sheak Rashed Haider Noori   +3 more
doaj  

Runtime Scheduling, Allocation, and Execution of Real-Time Hardware Tasks onto Xilinx FPGAs Subject to Fault Occurrence

International Journal of Reconfigurable Computing, 2013
This paper describes a novel way to exploit the computation capabilities delivered by modern Field-Programmable Gate Arrays (FPGAs), not only towards a higher performance, but also towards an improved reliability. Computation-specific pieces of circuitry
Xabier Iturbe, Khaled Benkrid, Chuan Hong, Ali Ebrahim, Tughrul Arslan, Imanol Martinez   +5 more
doaj   +1 more source

Assessing horizontal positional accuracy of Google Earth imagery in the city of Montreal, Canada

Geodesy and Cartography, 2017
The horizontal positional accuracy of Google Earth is assessed in the city of Montreal, Canada, using the precise coordinates of ten GPS points spatially distributed all over the city.
Mohammad Ali Goudarzi, René Jr. Landry
doaj   +1 more source