Results 111 to 120 of about 1,295,202 (338)

Semantic search using protein large language models detects class II microcins in bacterial genomes

mSystems
Class II microcins are antimicrobial peptides that have shown some potential as novel antibiotics. However, to date, only 10 class II microcins have been described, and the discovery of novel microcins has been hampered by their short length and high ...
Anastasiya V. Kulikova, Jennifer K. Parker, Bryan W. Davies, Claus O. Wilke   +3 more
doaj   +1 more source

Embeddings into c0

Topology and its Applications, 1994
AbstractWe present some generalizations and improvements of results due to I. Aharoni and P. Assouad on embeddings of separable metric spaces into c0.
openaire   +2 more sources

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Detecting Domain Names Generated by DGAs With Low False Positives in Chinese Domain Names

IEEE Access
Attackers are known to utilize domain generation algorithms (DGAs) to generate domain names for command and control (C&C) servers and facilitate the distribution of uniform resource locators within malicious software.
Huiju Lee, Jeong Do Yoo, Seonghoon Jeong, Huy Kang Kim   +3 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Radiation preparation of nano-oxide@microcrystalline cellulose and its adsorption and removal of trichloroacetic acid

Fushe yanjiu yu fushe gongyi xuebao
Trichloroacetic acid is a common nonvolatile byproduct of drinking water disinfection and poses carcinogenic risks to the human body. In this study, four types of nano-oxide@microcrystalline-cellulose-based adsorbents (P25@microcrystalline cellulose ...
FU Lili, WANG Zhijun, LIU Kun, TANG Dongxu, YANG Jinyu, CHEN Huangqin, LI Yuesheng   +6 more
doaj   +1 more source

ON THE USE OF POLARIZED LIGHT IN THE DETECTION AND INVESTIGATION OF SUTURE MATERIALS EMBEDDED IN THE TISSUES [PDF]

, 1920
M. J. Stewart
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

A Remaining Useful Life Prediction Method Considering the Dimension Optimization and the Iterative Speed

IEEE Access, 2019
Tool life prediction is critical to workpiece quality and machining costs. In this paper, a remaining useful life prediction method was proposed, which considering the dimension optimization accuracy of vibration features and the iterative speed of ...
Yiming Li, Xiangmin Meng, Zhongchao Zhang, Guiqiu Song   +3 more
doaj   +1 more source

Completion and Embedding of the Schwarzschild Solution [PDF]

, 1959
C. Frønsdal
openalex   +1 more source