Results 111 to 120 of about 1,342,763 (314)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

An embedding theorem for spaces of convex sets [PDF]

, 1952
Hans Rådström
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Completion and Embedding of the Schwarzschild Solution [PDF]

, 1959
C. Frønsdal
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

The linear projective element of a surface embedded in the space with a projective connection [PDF]

, 1958
Alois Švec
openalex   +1 more source

Embeddings into c0

Topology and its Applications, 1994
\textit{I. Aharoni} [Israel J. Math. 19(1974), 284-291 (1975; Zbl 0303.46012)] proved that each separable metric space can be Lipschitz embedded into \(c_0(\omega_0)\), \textit{P. Assouad} [ibid. 31, 97-100 (1978; Zbl 0387.54003)] simplified his proof, improved constants of Lipschitz embeddings and suggested a generalization of his result.
openaire   +3 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

One-to-One Embedding between Honeycomb Mesh and Petersen-Torus Networks

Sensors, 2011
As wireless mobile telecommunication bases organize their structure using a honeycomb-mesh algorithm, there are many studies about parallel processing algorithms like the honeycomb mesh in Wireless Sensor Networks.
Jung-Hyun Seo, Hyun Sim, Dae-Heon Park, Jang-Woo Park, Yang-Sun Lee   +4 more
doaj   +1 more source

Contribution to the Study of the Early Human Ovum based upon the investigation of I. A very early Ovum embedded in the Uterus and II. A very early Ovum embedded in the Infundibulum of the Tube. [PDF]

, 1914
Ricky W. Johnstone
openalex   +1 more source