Results 111 to 120 of about 1,397,905 (314)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The equivalence problem and rigidity for hypersurfaces embedded into hyperquadrics
, 2002 We consider the class of Levi nondegenerate hypersurfaces $M$ in $\bC^{n+1}$ that admit a local (CR transversal) embedding, near a point $p\in M$, into a standard nondegenerate hyperquadric in $\Bbb C^{N+1}$ with codimension $k:=N-n$ small compared to ...
Ebenfelt, P., Huang, X., Zaitsev, D.
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
2-biplacement without fixed points of (p,q)-bipartite graphs [PDF]
Opuscula Mathematica, 2005 In this paper we consider \(2\)-biplacement without fixed points of paths and \((p,q)\)-bipartite graphs of small size. We give all \((p,q)\)-bipartite graphs \(G\) of size \(q\) for which the set \(\mathcal{S}^{*}(G)\) of all \(2\)-biplacements of \(G\)
Beata Orchel
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
IEEE AccessInformation hiding in digital images is a critical technique for secure communication in the era of high-volume multimedia exchange. While many existing methods embed secret data by modifying image parameters in the spatial or frequency domains, they ...
Mohsin Shah +3 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
An Automatic Framework Recognizing the Relationships of Cultural Heritage
IEEE AccessThe field of cultural heritage has developed over a long period, accumulating a wealth of research findings. Researchers are now focusing on systematic relationships and taxonomic studies of heritage, exploring the underlying cultural information ...
Zizhan Zhang, Zijun Zhou, Yingchun Cao
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source