Results 91 to 100 of about 535,963 (306)
Topology and its Applications, 2013 In 2013, the authors introduced the notion of \(p\)-extension of rings [Contemporary Mathematics 609, 19--32 (2014; Zbl 1302.13012)]. An extension of rings \(R \hookrightarrow S\) is a \(p\)-extension if for each \(s\in S\) there is an \(r\in R\) such that \(sS = rS\).
Bhattacharjee, Papiya +2 more
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Applied SciencesIn this study, we employ machine learning techniques to improve materials in data scarcity conditions. In particular, we focus on the prediction of the cloud point temperatures of polymer–water systems with thermoresponsive behavior.
Marcela Elisabeth Penoff +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
<p>The logic embedding tool is a tool for embedding non-classical logics into classical logic (primarily higher-order logic (HOL), but also first-order logic in some cases). The tool translates a TPTP problem statement formulated in a non-classical
Steen, Alexander
core +1 more source
Physics Letters B, 2002 Using the embedded defect method, we classify the possible embeddings of a 't Hooft-Polyakov monopole in a general gauge theory. We then discuss some similarities with embedded vortices and relate our results to fundamental monopoles.
openaire +3 more sources
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source