Results 81 to 90 of about 300,587 (269)
, 2018 A single abstract from the DHd-2018 Book of Abstracts.
Fotis Jannidis, Mike Kestemont
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
, 2010 We initiate the study of on-line metric embeddings. In such an embedding we are given a sequence of n points X = x [subscript 1],...,x [subscript n] one by one, from a metric space M = (X,D). Our goal is to compute a low-distortion embedding of M into some host space, which has to be constructed in an on-line fashion, so that the image of each x i ...
Indyk, Piotr +3 more
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Discrete Mathematics, 2001 The author studies the problem of upward embedding on the round sphere and gives a characterization of all spherical digraphs.
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
GDRMA: Graph Neural Networks for Document Retrievals With Mean Aggregation
IEEE AccessWith the proliferation of cloud services and high-capacity hard drives, the volume of stored document data is rapidly increasing. Consequently, large-scale document retrieval tasks have been attracting significant attention.
Shigeru Maya
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Digital Content Security by Butterfly and Elliptic Curve Cryptography with Channel Optimization [PDF]
International Journal of Mathematical, Engineering and Management SciencesAs more and more services and solutions are utilizing digital data, it becomes imperative to provide strong security mechanisms to safeguard sensitive content with a rapidly growing number of users.
Kartikey Pandey, Deepmala Sharma
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