Results 81 to 90 of about 535,963 (306)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Sensors, 2015 The production of large and complex parts using fiber composite materials is costly due to the frequent formation of voids, porosity and waste products.
Maryam Kahali Moghaddam +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Is Embedding Entailed in Consumer Valuation of Food Safety Characteristics? [PDF]
Consumers’ preferences for food safety characteristics are investigated with particular focus on existence of an embedding effect. Embedding exists if consumer valuation of food safety is insensitive to scope.
Morkbak, Morten Raun +3 more
core
Embedding information skills on student learning: providing the models [PDF]
, 2007 This article was first published in the Wolverhampton Intellectual Repository and E-Theses (WIRE). There is no printed version.This Phase 3 (evaluation and embedding) project has been developed from a highly successful earlier project: Embedding ...
Bastable, Wendy, Morris, Pamela
core +2 more sources
LLM-Enhanced Semantic Text Segmentation
Applied SciencesThis study investigates semantic text segmentation enhanced by large language model (LLM) embeddings. We assess how effectively embeddings capture semantic coherence and topic closure by integrating them into both classical clustering algorithms and a ...
Alexander Krassovitskiy +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Reversible watermarking scheme with image-independent embedding capacity [PDF]
Permanent distortion is one of the main drawbacks of all the irreversible watermarking schemes. Attempts to recover the original signal after the signal passing the authentication process are being made starting just a few years ago. Some common problems,
Li, Chang-Tsun
core
Modal Adverbs in FDG: Putting the Theory to the Test
Open Linguistics, 2018 One of the distinctive features of the theory of Functional Discourse Grammar (FDG) is that it distinguishes various hierarchically organized layers of analysis, each of which is provided with a slot for modifiers relevant at the layer in question ...
Keizer Evelien
doaj +1 more source