Results 111 to 120 of about 535,963 (306)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

KennethEnevoldsen/scandinavian-embedding-benchmark: v0.9.0

<h1>v0.9.0 (2024-01-26)</h1> <h2>Feature</h2> <ul> <li>feat: Added performance metrics for danfever (<a href="https://github.com/KennethEnevoldsen/scandinavian-embedding-benchmark/commit ...
Márton Kardos, Lasse Hansen, Tim Isbister, Kenneth Enevoldsen   +3 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

KennethEnevoldsen/scandinavian-embedding-benchmark: v0.3.1

<h1>v0.3.1 (2024-01-15)</h1> <h2>Documentation</h2> <ul> <li>docs: added execute flag (<a href="https://github.com/KennethEnevoldsen/scandinavian-embedding-benchmark/commit/ea0e9ca6329a062c229d6157005f68cca4b98f15 ...
Lasse Hansen, Márton Kardos, Tim Isbister, Kenneth Enevoldsen   +3 more
core   +1 more source

2-biplacement without fixed points of (p,q)-bipartite graphs [PDF]

Opuscula Mathematica, 2005
In this paper we consider \(2\)-biplacement without fixed points of paths and \((p,q)\)-bipartite graphs of small size. We give all \((p,q)\)-bipartite graphs \(G\) of size \(q\) for which the set \(\mathcal{S}^{*}(G)\) of all \(2\)-biplacements of \(G\)
Beata Orchel
doaj  

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

KennethEnevoldsen/scandinavian-embedding-benchmark: v0.3.0

<h1>v0.3.0 (2024-01-14)</h1> <h2>Ci</h2> <ul> <li>ci: Updated some names in the workflow (<a href="https://github.com/KennethEnevoldsen/scandinavian-embedding-benchmark/commit ...
Lasse Hansen, Márton Kardos, Tim Isbister, Kenneth Enevoldsen   +3 more
core   +1 more source

Digraph embedding

Discrete Mathematics, 2001
The author studies the problem of upward embedding on the round sphere and gives a characterization of all spherical digraphs.
openaire   +3 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source