Results 131 to 140 of about 1,397,905 (314)
Node Embeddings via Neighbor Embeddings
Accepted to Transactions of Machine Learning Research (TMLR)
Böhm, Jan Niklas +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
AlgorithmsThe judicious configuration of predicates is a crucial but often overlooked aspect in the field of knowledge graphs. While previous research has primarily focused on the precision of triples in assessing knowledge graph quality, the rationality of ...
Xin Tian, Yuan Meng
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
GLOCALIZATION, EMBEDDING, ANCHORING: ON THE COGNITIVE IMPACT AND EXPERIENCE OF GLOBALIZATION
Glocalism: Journal of Culture, Politics and InnovationThis essay discusses globalization and glocalization as crucially important concepts for the Social Sciences and Humanities, thereby distinguishing between globalization/ glocalization as research methodology (hermeneutics) and as historical process ...
MIGUEL JOHN VERSLUYS
doaj +1 more source
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Direct Analysis and MALDI Imaging of Formalin-Fixed, Paraffin-Embedded Tissue Sections
, 2007 R. Lemaire +5 more
openalex +2 more sources
Let’s embed peer-support groups into the medical curriculum for all [PDF]
, 2021 Aisling Higham +5 more
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar +3 more
wiley +1 more source