Results 131 to 140 of about 1,342,763 (314)
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
IEEE AccessInformation hiding in digital images is a critical technique for secure communication in the era of high-volume multimedia exchange. While many existing methods embed secret data by modifying image parameters in the spatial or frequency domains, they ...
Mohsin Shah +3 more
doaj +1 more source
A flat Klein bottle isometrically embedded in euclidean 4-space [PDF]
, 1941 Casey Tompkins
openalex +1 more source
Molecular Oncology, EarlyView.This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga +8 more
wiley +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
LLM-Enhanced Semantic Text Segmentation
Applied SciencesThis study investigates semantic text segmentation enhanced by large language model (LLM) embeddings. We assess how effectively embeddings capture semantic coherence and topic closure by integrating them into both classical clustering algorithms and a ...
Alexander Krassovitskiy +2 more
doaj +1 more source
Embeddings of projective spaces into elliptic projective Lie groups [PDF]
, 1959 Ichiro Yokota
openalex +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
2-biplacement without fixed points of (p,q)-bipartite graphs [PDF]
Opuscula Mathematica, 2005 In this paper we consider \(2\)-biplacement without fixed points of paths and \((p,q)\)-bipartite graphs of small size. We give all \((p,q)\)-bipartite graphs \(G\) of size \(q\) for which the set \(\mathcal{S}^{*}(G)\) of all \(2\)-biplacements of \(G\)
Beata Orchel
doaj
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source