Results 41 to 50 of about 12,318 (293)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Embodied carbon costs of prefabricated substation buildings

open access: yesLow-Carbon Materials and Green Construction
Exploring the economic impacts of embodied carbon emissions is significant for achieving sustainable development in construction projects. However, the quantitative assessment of carbon costs in prefabricated buildings remains lacking.
Xilong Chen   +3 more
doaj   +1 more source

Scrutinising embodied carbon in buildings: The next performance gap made manifest [PDF]

open access: yes, 2017
Life cycle assessment (LCA) is becoming increasingly mainstream as an early-stage design-decision tool for buildings. Still, there are considerable variations in how the method is currently used, leading to limitations in comparing the results and the ...
Pomponi, Francesco   +3 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Evaluating the embodied carbon emissions of power infrastructure construction towards carbon neutrality: A study of Fujian province, China

open access: yesEnergy Strategy Reviews
The transformation of the power sector toward renewable energy is crucial for achieving China's carbon neutrality goals and mitigating global climate change.
Zewen Ge   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Impact of China’s embedding in RCEP regional value chain on embodied carbon emissions from agricultural product exports [PDF]

open access: yesZiyuan Kexue
[Objective] Reducing the embodied carbon emissions from agricultural product exports is of great significance for agricultural carbon emission reduction.
ZHANG Mei, ZHOU Jiaxuan
doaj   +1 more source

Embodied CO2 Emission Changes in Manufacturing Trade: Structural Decomposition Analysis of China, Japan, and Korea

open access: yesAtmosphere, 2020
This study investigated the driving factors of embodied carbon emission changes in manufacturing trades through structural decomposition analysis. For empirical analysis, we developed an environmental multiregional input–output model for Korea, Japan ...
Young Yoon, Yoon-Kyung Kim, Jinsoo Kim
doaj   +1 more source

Study on the characteristics of embodied carbon emission transfer in China’s power sector based on input-output networks

open access: yesFrontiers in Environmental Science, 2023
Electricity is an essential factor of production. The trade of goods and services between different industrial sectors in different regions may lead to the transfer of embodied carbon emissions in the power sector, which makes the problem of “carbon ...
Xiaodi Ma   +7 more
doaj   +1 more source

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