Results 41 to 50 of about 7,314 (254)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Analisis Konsumsi Embodied Energy dan Embodied Carbon pada Material Bangunan Rumah Sederhana Tipe 36

open access: yesTeknik, 2021
Sektor perumahan merupakan kebutuhan pokok bagi setiap orang. Setiap negara berupaya untuk memenuhi kebutuhan rumah bagi warganya, salah satunya di Indonesia yang memprogramkan satu juta rumah bagi masyarakat miskin.
Subrata Aditama K.A. Uda
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

A comprehensive tool for embodied carbon quantification and supporting mitigation strategies in the Building sector

open access: yesDiscover Applied Sciences
The building sector is a significant contributor to global greenhouse gas (GHG) emissions, with emissions classified into operational and embodied carbon.
Miguel Martinho   +4 more
doaj   +1 more source

Study on the characteristics of embodied carbon emission transfer in China’s power sector based on input-output networks

open access: yesFrontiers in Environmental Science, 2023
Electricity is an essential factor of production. The trade of goods and services between different industrial sectors in different regions may lead to the transfer of embodied carbon emissions in the power sector, which makes the problem of “carbon ...
Xiaodi Ma   +7 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The Inter-Regional Embodied Carbon Flow Pattern in China Based on Carbon Peaking Stress

open access: yesEnergies
Embodied carbon flows among regions have led to unfair carbon emission responsibility accounting based on production. However, the heterogeneity of carbon peaking stress between regions is significantly neglected for those embodied carbon flows ...
Qianqian Xiao   +2 more
doaj   +1 more source

Managing embodied carbon in buildings: a Pareto approach [PDF]

open access: yesBuilt Environment Project and Asset Management, 2018
PurposeThe purpose of this paper is to identify the carbon intensive building elements or “carbon hotspots” of office buildings in order to maximise the carbon reduction potential during design stages.Design/methodology/approachEmbodied carbon (EC) estimates of 28 office buildings in the UK were obtained and carbon hotspots of the sample (in accordance
Victoria, Michele   +1 more
openaire   +3 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Life cycle carbon emissions and comparative evaluation of selected open source UK embodied carbon counting tools

open access: yesConstruction Economics and Building, 2019
Life cycle carbon emissions (LCO2), made up of operational and embodied carbon, have become a major metric of building environmental performance and energy efficiency.
Damilola Ekundayo   +4 more
doaj  

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