Results 61 to 70 of about 2,359,808 (286)

The Inter-Regional Embodied Carbon Flow Pattern in China Based on Carbon Peaking Stress

open access: yesEnergies
Embodied carbon flows among regions have led to unfair carbon emission responsibility accounting based on production. However, the heterogeneity of carbon peaking stress between regions is significantly neglected for those embodied carbon flows ...
Qianqian Xiao   +2 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Life cycle carbon emissions and comparative evaluation of selected open source UK embodied carbon counting tools

open access: yesConstruction Economics and Building, 2019
Life cycle carbon emissions (LCO2), made up of operational and embodied carbon, have become a major metric of building environmental performance and energy efficiency.
Damilola Ekundayo   +4 more
doaj  

Improving the buildings' sustainability through combined matrix assessment of embodied energy, water, and carbon: case of conventional houses, Jammu-India

open access: yesJournal of Sustainable Development of Energy, Water and Environment Systems
The study attempts the comparatives of embodied energy, water, and carbon parameters in the cradle-to-gate phase of building construction for conventional houses in Jammu, India.
Anoop Kumar Sharma, Prabhjot Singh Chani
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Managing embodied carbon in buildings: a Pareto approach [PDF]

open access: yesBuilt Environment Project and Asset Management, 2018
PurposeThe purpose of this paper is to identify the carbon intensive building elements or “carbon hotspots” of office buildings in order to maximise the carbon reduction potential during design stages.Design/methodology/approachEmbodied carbon (EC) estimates of 28 office buildings in the UK were obtained and carbon hotspots of the sample (in accordance
Victoria, Michele   +1 more
openaire   +3 more sources

Embodied carbon emissions of buildings and how to tame them

open access: yes, 2023
Building construction and operations are pivotal in climate mitigation efforts. While emissions from building operations can be easily reduced through renewable energy adoption and improved energy efficiency, the so-called “embodied” greenhouse gas (GHG)
Saade, Marcella Ruschi Mendes   +3 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Statistical characterization and prediction of embodied carbon in reinforced concrete buildings for low-carbon design

open access: yesCase Studies in Construction Materials
With the rapid expansion of the construction sector, reducing embodied carbon in reinforced concrete (RC) buildings has become an important issue for low-carbon development.
Fan Zhang   +6 more
doaj   +1 more source

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