Results 41 to 50 of about 24,126 (285)

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker   +11 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Embodied AI as Science: Models of Embodied Cognition, Embodied Models of Cognition, or Both?

open access: yes, 2004
This paper discusses the identity of embodied AI, i.e. it asks the question exactly what it is that makes AI research embodied. From an engineering perspective, it is fairly clear that embodied AI is about robotic, i.e. physically embodied systems.
Tom Ziemke, Ziemke, Tom,
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Does the Level of Temporal Demand Affect Activation of the Mental Timeline?

open access: yesJournal of Cognition
The space-time congruency effect indicates faster processing of past-/future-related words with the left/right response key, suggesting the presence of the horizontal Mental Time Line (MTL).
Katharina Kühne   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Embodied cognition: looking inward [PDF]

open access: yes, 2017
The body is a highly complex, coordinated system engaged in coping with many environmental problems. It can be considered as some sort of opportunity or obstacle, with which internal processing must deal.
Nowakowski, Przemysław R.
core   +2 more sources

Horizontal mapping of time-related words in first and second language

open access: yesScientific Reports
The existence of a consistent horizontal spatial-conceptual mapping for words denoting time is a well-established phenomenon. For example, words related to the past or future (e.g., yesterday/tomorrow) facilitate respective leftward/rightward attentional
Anastasia Malyshevskaya   +3 more
doaj   +1 more source

Embodied Cognitive Science, Aesthetics, and the Study of Visual Language [PDF]

open access: yesThe Polish Journal of Aesthetics, 2019
The paradigm of embodied cognition provides a perspective for rethinking the nature of experience, intersubjectivity, and the interaction of the human animal with its physical and sociocultural environments. Embodied cognitive science can be a productive
David Charles Wright-Carr
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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