Results 51 to 60 of about 1,005,803 (349)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Re-investigating the shared responsibility for trade-embodied carbon emissions [PDF]

The distribution of trade-embodied carbon emissions has frequently been a contestation in international climate negotiations. The proposed shared responsibility approach developed by Jakob et al.
Ji, Chang Jing, Liu, Yu, Wei, Yi Ming, Wang, Ke, Shan, Yuli; id_orcid, Wang, Jiayu, Ji, Chang-Jing, Hubacek, Klaus, Hubacek, Klaus; id_orcid   +8 more
core   +1 more source

Decomposition of factors affecting embodied waste gas emissions (unit: 100 million cubic meters).

, 2022
Decomposition of factors affecting embodied waste gas emissions (unit: 100 million cubic meters).
Yu-Xia Du (14053632), Ming-Jie Li (9355613), Jun-Jie Huang (662124)   +2 more
core   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

A comprehensive tool for embodied carbon quantification and supporting mitigation strategies in the Building sector

Discover Applied Sciences
The building sector is a significant contributor to global greenhouse gas (GHG) emissions, with emissions classified into operational and embodied carbon.
Miguel Martinho, Joana Fernandes, Ricardo Gomes, Paulo Lourador, Paulo Ferrão   +4 more
doaj   +1 more source

Material requirements for future low-carbon electricity projections in Africa

Energy Strategy Reviews, 2022
Deploying low-carbon electricity systems in developing countries is critical for meeting climate targets while increasing wellbeing. Direct emissions from operating electricity generation are well-understood, however, materials required to construct ...
Karla Cervantes Barron, Maaike E. Hakker, Jonathan M. Cullen   +2 more
doaj   +1 more source

Embodied Carbon Emissions

The United Nation (UN) projects that 2.5 billion more people will live in cities by 2050, up from 4.4 billion today. Of the growing global population, most will come from the urban areas of low- and middle-income countries in Sub-Saharan Africa and South Asia, with Sub-Saharan African cities currently already seeing a 4.1 percent growth in population ...
Chen, Tao, Deuskar, Chandan
openaire   +2 more sources

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source