Results 51 to 60 of about 70,425 (308)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Material requirements for future low-carbon electricity projections in Africa

Energy Strategy Reviews, 2022
Deploying low-carbon electricity systems in developing countries is critical for meeting climate targets while increasing wellbeing. Direct emissions from operating electricity generation are well-understood, however, materials required to construct ...
Karla Cervantes Barron, Maaike E. Hakker, Jonathan M. Cullen   +2 more
doaj   +1 more source

Embodied Carbon Emissions

The United Nation (UN) projects that 2.5 billion more people will live in cities by 2050, up from 4.4 billion today. Of the growing global population, most will come from the urban areas of low- and middle-income countries in Sub-Saharan Africa and South Asia, with Sub-Saharan African cities currently already seeing a 4.1 percent growth in population ...
Chen, Tao, Deuskar, Chandan
openaire   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A comprehensive tool for embodied carbon quantification and supporting mitigation strategies in the Building sector

Discover Applied Sciences
The building sector is a significant contributor to global greenhouse gas (GHG) emissions, with emissions classified into operational and embodied carbon.
Miguel Martinho, Joana Fernandes, Ricardo Gomes, Paulo Lourador, Paulo Ferrão   +4 more
doaj   +1 more source

Optimizing building solutions in a changing climate: parameter-based analysis of embodied and operational environmental impacts

Environmental Research: Infrastructure and Sustainability, 2023
Buildings contribute significantly to global energy consumption and carbon dioxide emissions. Climate change affects building performance, particularly heating and cooling demands. While current policies focus on improving energy performance and reducing
Delphine Ramon, Karen Allacker
doaj   +1 more source

Border carbon adjustments: Addressing emissions embodied in trade [PDF]

Energy Policy, 2016
Approximately one fourth of global emissions are embodied in international trade and a significant portion flows from non-carbon-priced to carbon-priced economies. Border carbon adjustments (BCAs) figure prominently as instruments to address concerns arising from unilateral climate policy.
Sakai, M, Barrett, J
openaire   +2 more sources

Domestic UK retrofit challenge: Barriers, incentives and current performance leading into the green deal [PDF]

, 2012
Copyright @ 2012 Elsevier - The official published version can be accessed from the link below.This paper reviews the thermal performance of the existing UK housing stock, the main fabric efficiency incentive schemes and the barriers to obtaining deep ...
Dowson, M, Harrison, DJ, Poole, A, Susman, G   +3 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Spatial-temporal changes of land-use mercury emissions in China

Ecological Indicators, 2023
Land use change is closely related to human activities, and has significant impacts on pollutant emissions. Mercury (Hg) is the most toxic heavy metal element gas damaging the environment severely, and China has the largest mercury emissions.
Shan Guo, Yang Wang
doaj   +1 more source