Results 51 to 60 of about 360,665 (306)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An investigation into standards in sustainable design and manufacture [PDF]

, 2009
This paper reports upon the application of standards to reduce the negative environmental impacts of manufacturing through product lifecycle planning and closed loop production. By eliminating waste and retaining the energy embodied within materials and
Griffiths, BJ, Harrison, DJ, Lam, B, Plant, AVC   +3 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Embodied Energy Audit of Residential Building [PDF]

, 2016
Buildings consume a vast amount of energy during the life cycle stages of construction, use and demolition. Total life cycle energy use in a building consists of two components: embodied and operational energy.
Mali, M. A. (Mr), Waghmare, P. A. (Prof)
core  

Life cycle carbon emissions and comparative evaluation of selected open source UK embodied carbon counting tools [PDF]

, 2019
Life cycle carbon emissions (LCO2), made up of operational and embodied carbon, have become a major metric of building environmental performance and energy efficiency.
Babatunde, S.O., Babatunde, S.O., Ekundayo, A., Ekundayo, A., Ekundayo, D., Ekundayo, D., Perera, S., Perera, S., Udeaja, C., Udeaja, C.   +9 more
core   +5 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Improving the buildings' sustainability through combined matrix assessment of embodied energy, water, and carbon: case of conventional houses, Jammu-India

Journal of Sustainable Development of Energy, Water and Environment Systems
The study attempts the comparatives of embodied energy, water, and carbon parameters in the cradle-to-gate phase of building construction for conventional houses in Jammu, India.
Anoop Kumar Sharma, Prabhjot Singh Chani
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Comparing construction technologies of single family housing with regard of minimizing embodied energy and embodied carbon

E3S Web of Conferences, 2018
This article concerns the Life Cycle Assessment method of evaluation and the ways in which it can be applied as a tool facilitating the design of buildings to reduce embodied energy and embodied carbon. Three variants of a building were examined with the
Węglarz Arkadiusz, Pierzchalski Michał
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source