Results 71 to 80 of about 14,187,311 (335)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Embodied Energy and Off-Grid Lighting [PDF]

, 2011
The greenhouse gas (GHG) emissions from fuel-based lighting are substantial given the paltry levels of lighting service provided to users, leading to a great opportunity for GHG mitigation byencouraging the switch from fuel-based to rechargeable LED ...
Alstone, Peter, Mills, Evan, Jacobson, Arne   +2 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Is embodied carbon a vanity metric? [PDF]

An article for influential professional journal Architects' Journal, arguing that embodied energy should be monitored for construction or retrofit projects alongside embodied ...
Urban, Florian, Calder, Barnabas
core   +1 more source

Towards Sustainable Conventional Indian Houses: Linking Embodied Water-Energy Nexus to Pro-locals’ Architecture, Construction and Regulatory Reforms with Lifecycle Assessment and Scenarios Methods

Journal of Sustainable Development of Energy, Water and Environment Systems
Real-world insights to conserve water in constructions without overshooting embodied energy meet sustainable development goal 12, specifically in the current thirsty world.
Anoop Kumar Sharma, Prabhjot Singh Chani, Atul Anand Jha   +2 more
doaj   +1 more source

The effect of climatic design of the building on the reduction of Embodied energy and comparison with the consumed electricity (A case-study of Shiraz city)

تحلیل مدارها، داده ها و سامانه ها
This research has evaluated the reduction of embodied energy consumption in the building (energy consumed during construction) and comparing it with energy consumption during the exploitation period (electricity consumption).
Azar Zinali-kharagy, Maryam Haghpanah
doaj   +1 more source

Embodied Energy in Building Construction

Jurnal Teknologi, 2014
Building construction systems that come in different forms and types need to be properly selected before being use, this may have different impact on overall embodied energy of the building construction. Hence, in order to achieve and maximize the construction contribution, the designer plays a big role in choosing the appropriate energy efficient ...
Balubaid, Saeed, Mohamad Zin, Rosli, Abd. Majid, Muhd. Zaimi, Hassan, J. S., Mardzuki, Samihah   +4 more
openaire   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Comparing construction technologies of single family housing with regard of minimizing embodied energy and embodied carbon

E3S Web of Conferences, 2018
This article concerns the Life Cycle Assessment method of evaluation and the ways in which it can be applied as a tool facilitating the design of buildings to reduce embodied energy and embodied carbon. Three variants of a building were examined with the
Węglarz Arkadiusz, Pierzchalski Michał
doaj   +1 more source

Evaluating the impact of operating energy reduction measures on embodied energy

Energy and Buildings, 2020
Annually, 48% of the global energy is used by buildings in their construction, operation, and maintenance, causing significant damage to the environment due to the resulting greenhouse gas emissions.
V. Venkatraj, M. Dixit, Wei Yan, S. Lavy
semanticscholar   +1 more source