Results 201 to 210 of about 588,441 (286)
ABSTRACT Background and Aims Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, encompassing coronary artery disease, hypertension, heart failure, and cerebrovascular disorders. The global burden of CVD continues to rise, driven by complex interactions among endothelial dysfunction, oxidative stress, inflammation,
Nawfal Hasan Siam +8 more
wiley +1 more source
A probiotic‐enriched BioHybrid hydrogel that provides sustained O2, probiotic metabolites, and pH‐responsive anti‐cancer drug is reported. This BioHybrid hydrogel promotes healthy cell viability while reducing ROS and decreases cancer cell viability while increasing ROS under hypoxia conditions. The co‐administration of O2, metabolites, and drug from a
Ulvi Süleymanzade +4 more
wiley +1 more source
Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait +5 more
wiley +1 more source
In hepatocellular carcinoma (HCC) cells exposed to doxorubicin, DUSP12 depletion maintains NAT10 phosphorylation, reducing its acetyltransferase activity, which leads to reduced ac4C RNA acetylation, DNA damage response, and DNA break repair, with consequent tumor sensitization.
Viktor Kalbermatter Boell +6 more
wiley +1 more source
Neurocardiology: Brain–Heart Interactions in the Heart
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang +3 more
wiley +1 more source
Applications of Mesenchymal Stromal Cells for Treatment of Diseases
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley +1 more source
Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source
Long‐Term Chronological Changes of Liver Stiffness After Hepatic Rupture: A Case Report
ABSTRACT Background Shear wave elastography (SWE) was originally developed to assess the staging of fibrosis caused by chronic liver diseases, including chronic hepatitis B and C and metabolic dysfunction‐associated steatotic liver disease. However, it has not been previously used to evaluate traumatic liver injury.
Hisayo Okazaki +10 more
wiley +1 more source
Development of the abdominal musculature in the chicken embryo
In this study, we investigate anatomy, morphogenesis, segmental origin, and fiber formation of the abdominal musculature in the chicken embryo. We show that abdominal muscles arise from somites 24 to 28, and that the segmental identity of individual fibers in the abdominal muscle sheets is maintained.
Margarethe Draga +6 more
wiley +1 more source
Fat Embolism Syndrome: A Case Series from a Single Tertiary Care Hospital. [PDF]
Borgohain B, Naveen AS, Khonglah TG.
europepmc +1 more source

