Results 71 to 80 of about 479,170 (304)

Embolic stroke of unknown source (ESUS) in patients with atrial septum defect and patent foramen ovale: difference and similarities [PDF]

, 2015
Introduction Paradoxical embolism from right-to-left shunt through a patent foramen ovale (PFO) is a well-characterized cause of embolic strokes of undetermined source (ESUS).
DELABAYS, C.
core  

Epidemiology of Myocardial Infarction Caused by Presumed Paradoxical Embolism via a Patent Foramen Ovale.

Circulation Journal, 2017
BACKGROUND Despite several negative prospective randomized trials on the efficacy of patent foramen ovale (PFO) occlusion, the discussion on indications is ongoing.
F. Kleber, Telse Hauschild, A. Schulz, Anne Winkelmann, L. Bruch   +4 more
semanticscholar   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

Paradoxical emboli from calf and pelvic veins in cryptogenic stroke. [PDF]

, 2003
PURPOSE: The increased prevalence of patent foramen ovale in patients with cryptogenic strokes suggests the occurrence of paradoxical embolism. The identification of deep venous thromboses (DVTs) in this population would strengthen this hypothesis.
Burgin, W Scott, Cramer, Steven C, D'Souza, Neisha, Grotta, James C, Kramer, Larry A, Maki, Jeffrey H, Waitches, Gayle M   +6 more
core   +1 more source

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension [PDF]

, 2015
The effects of increased intra-abdominal pressure (IAP) on cardiovascular function are well recognized and include a combined negative effect on preload, afterload and contractility.
De Keulenaer, Bart L, De Waele, Jan, Malbrain, Manu LNG   +2 more
core   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Multidisciplinary Management for Concomitant High-Risk Pulmonary Embolism and Large-Vessel Occlusion Stroke From Paradoxical Embolism

Annals of Internal Medicine: Clinical Cases
Concurrent pulmonary embolism (PE) and acute ischemic stroke are uncommon but associated with high morbidity. Paradoxical embolism occurs when thrombi cross right-to-left cardiac/pulmonary shunts such as a patent foramen ovale.
Phuong-Uyen Vo, Mark Rea, Justin Dunn, Aashish Anand, Madihah Hepburn   +4 more
doaj   +1 more source

Patent Foramen Ovale and Stroke–Current Status [PDF]

Journal of Stroke, 2015
Patent foramen ovale (PFO) is growing in clinical interest because of a renewed focus on embolic stroke of undetermined source (ESUS), the PFO attributable fraction (the 10-point Risk of Paradoxical Embolism score), technical advances in PFO diagnosis ...
Oh Young Bang, Mi Ji Lee, Sookyung Ryoo, Suk Jae Kim, Ji Won Kim   +4 more
doaj   +1 more source

Ischaemic strokes in patients with pulmonary arteriovenous malformations and hereditary hemorrhagic telangiectasia: associations with iron deficiency and platelets. [PDF]

, 2014
BackgroundPulmonary first pass filtration of particles marginally exceeding ∼7 µm (the size of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming or entering the circulation in the preceding cardiac cycle to lodge ...
AD Kjeldsen, AD Kjeldsen, AE Guttmacher, AJ Easey, B Barzilai, B Nieswandt, Basel Chamali, BD Butler, BJ Folz, BM Silva, C Coupland, C Shovlin, CJ Gallione, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, CL Shovlin, Claire L. Shovlin, DW Johnson, E Buscarini, ER Chilvers, ER Weibel, F Roked, Gillian Angus, H Finnamore, Hannah C. Tighe, HL Devlin, IS Anand, J Feinstein, J Parra, J Remy, JA Dutton, JA Feinstein, JA Livesey, James E. Jackson, JE Van de Pette, JJ Mager, JL Hart, John A. Livesey, John Meek, K Clark, K Hara, K Nanthakumar, K Ono, K Zukotynski, KL Furie, Klaus Brusgaard, LC Weng, LS Valberg, M Bajc, M Billinger, M Blomley, M Moussouttas, M Nakayama, M Yeung, ME Faughnan, Michael A. Laffan, MK Whyte, MW van Gent, MW van Gent, OS AAssar, P Gazzaniga, P Gupta, P Shovlin CL, Wilmshurst, PC Hébert, RD Thompson, RF Gillum, Richard Manning, S Jackson, S Uchiyama, S Velthuis, SM Bang, T Krings, T Ueki, V Cottin, Vatshalan Santhirapala, WB Porter, Y Benjamini, Y Shinohara, Z Hao   +83 more
core   +3 more sources

Cerebral Infarction by Paradoxical Gas Embolism During Laparoscopic Liver Resection with Injury of the Hepatic Vessels in a Patient without a Right-to-Left Systemic Shunt

The American journal of case reports, 2017
Patient: Male, 60 Final Diagnosis: Hepatocellular carcinoma Symptoms: None Medication: — Clinical Procedure: Hepatectomy Specialty: Surgery Objective: Unusual clinical course Background: Carbon dioxide (CO2) is believed to be the safest gas for ...
T. Kawahara, M. Hagiwara, Hiroyuki Takahashi, Mariko Tanaka, K. Imai, J. Sawada, T. Kunisawa, H. Furukawa   +7 more
semanticscholar   +1 more source