Results 81 to 90 of about 7,179 (184)
Cancer, Volume 131, Issue 18, 15 September 2025.Abstract Background The influence of obesity and sex on outcomes in pancreatic adenocarcinoma (PDAC) remains unclear. The association between obesity (body mass index [BMI], ≥30) and biologic sex (male or female) for outcomes in patients with PDAC undergoing a surgery‐first approach was investigated. Methods A prospectively maintained pancreatic cancer
Sean J. Judge +15 more
wiley +1 more source
Single‐Cell RNA Sequencing Delineates Renal Anti‐Fibrotic Mechanisms Mediated by TRPC6 Inhibition
Advanced Science, Volume 12, Issue 33, September 4, 2025.Single‐cell transcriptomics reveals how TRPC6 inhibition alters renal cell composition and gene expression in CKD. The study uncovers a novel endothelial subpopulation (ECRIN), highlights key inflammatory and fibrotic pathways, and identifies a Prnp‐driven network linked to fibrosis resolution, offering mechanistic insight into TRPC6 as a potential ...
Yao Xu +12 more
wiley +1 more source
Fatal Paradoxical Coronary Embolism [PDF]
Journal of the Royal Army Medical Corps, 1996 A case of a 53 year old man with fatal paradoxical coronary emboli is presented and the literature reviewed.
openaire +3 more sources
Catheterization and Cardiovascular Interventions, Volume 106, Issue 3, Page 2037-2047, September 1, 2025.ABSTRACT The patent foramen ovale (PFO), present in 25% of the population, can cause paradoxical embolism and stroke. Transcatheter PFO closure is the gold standard for recurrent embolism with significant inter‐atrial shunting, with recent trials confirming its superiority in reducing ischemic stroke recurrence over medical therapy.
Eirini Beneki +13 more
wiley +1 more source
Clinical characteristics and follow-up results of 12 cases of paradoxical embolism
Data in Brief, 2017 This article contains the clinical characteristics of the paradoxical embolized patients and the following up results. Data included are related to the article “Paradoxical embolism: Experiences from a single center” (Zhang Hong-liang, Liu Zhi-hong, Luo ...
Hong-liang Zhang +5 more
doaj +1 more source
Menthol and Its Derivatives: Exploring the Medical Application Potential
Engineering in Life Sciences, Volume 25, Issue 9, September 2025.ABSTRACT Menthol, a natural organic compound and the primary component of mint, exhibits diverse biological activities, including analgesic, anti‐inflammatory, antibacterial, neuroprotective, and anticancer effects. The chemical modification of menthol, through processes such as esterification and amination, further enhances these activities, expanding
Jing Zhang, Yupei Hu, Zheng Wang
wiley +1 more source
MedComm, Volume 6, Issue 9, September 2025.This graphical abstract summarizes the effects of ionizing radiation (IR) on epithelial–mesenchymal transition (EMT), emphasizing critical processes such as DNA damage repair, tumor microenvironment interactions, and resistance mechanisms. It highlights EMT‐induced radioresistance regulators, such as TGF‐β, Wnt, Notch, ERK, and various miRNAs, as well ...
Dhasarathdev Srinivasan +7 more
wiley +1 more source
Paradoxical embolism of a shotgun pellet
The Annals of Thoracic Surgery, 1998 Paradoxical embolism of a projectile from the venous to arterial system is a rare occurrence, which can cause diagnostic confusion. We present a case of venous embolism of a shotgun pellet from the left upper extremity to the noncoronary sinus of the aortic valve across a secundum-type atrial septal defect.
Steven J. Nisco +3 more
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MedComm – Oncology, Volume 4, Issue 3, September 2025.TGF‐β inhibition is emerging as a promising cancer therapy, yet translating laboratory success to bedside implementation has suffered significant setbacks. The associated challenges include adverse drug reactions, inadequate predictive models, and activation of alternative signaling pathways.
Faizah A. Alabi +5 more
wiley +1 more source