Results 71 to 80 of about 468,611 (425)

Computerized Tomography Pulmonary Angiography Image Simulation using Cycle Generative Adversarial Network from Chest CT imaging in Pulmonary Embolism Patients [PDF]

open access: yesarXiv, 2022
The purpose of this research is to develop a system that generates simulated computed tomography pulmonary angiography (CTPA) images clinically for pulmonary embolism diagnoses. Nowadays, CTPA images are the gold standard computerized detection method to determine and identify the symptoms of pulmonary embolism (PE), although performing CTPA is harmful
arxiv  

The watering of tall trees - Embolization and recovery [PDF]

open access: yesJournal of Theoretical Biology, Elsevier, 2015, 369, pp.42 - 50, 2014
We can propound a thermo-mechanical understanding of the ascent of sap to the top of tall trees thanks to a comparison between experiments associated with the cohesion-tension theory and the disjoining pressure concept for liquid thin-films. When a segment of xylem is tight-filled with crude sap, the liquid pressure can be negative although the ...
arxiv   +1 more source

Fibrinolysis for patients with intermediate-risk pulmonary embolism.

open access: yesNew England Journal of Medicine, 2014
BACKGROUND The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. METHODS In a randomized, double-blind trial, we compared tenecteplase plus heparin with placebo plus heparin in normotensive patients ...
G. Meyer   +36 more
semanticscholar   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Diagnosis, Treatment and Follow Up of Acute Pulmonary Embolism: Consensus Practice from the PERT Consortium

open access: yesClinical and applied thrombosis/hemostasis, 2019
Pulmonary embolism (PE) is a life-threatening condition and a leading cause of morbidity and mortality. There have been many advances in the field of PE in the last few years, requiring a careful assessment of their impact on patient care.
B. Rivera-Lebron   +33 more
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Heparin and air filters reduce embolic events caused by intra-arterial cerebral angiography - A prospective, randomized trial [PDF]

open access: yes, 2004
Background-Intra-arterial cerebral angiography is associated with a low risk for neurological complications, but clinically silent ischemic events after angiography have been seen in a substantial number of patients.Methods and Results-In a prospective ...
Bartsch, AJ   +8 more
core   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Venous Thromboembolism in Metastatic Uterine Leiomyosarcoma: A Case Report and Review of the Literature

open access: yesCase Reports in Oncology, 2023
We report an unusual case of extensive deep vein thrombosis (DVT) and pulmonary embolism (PE) in the setting of metastatic uterine leiomyosarcoma. Recognition of the associated sequelae of this condition may improve short- and long-term outcomes.
Austin R. Swisher   +7 more
doaj   +1 more source

Pregnancy‐Adapted YEARS Algorithm for Diagnosis of Suspected Pulmonary Embolism

open access: yesNew England Journal of Medicine, 2019
BACKGROUND Pulmonary embolism is one of the leading causes of maternal death in the Western world. Because of the low specificity and sensitivity of the D‐dimer test, all pregnant women with suspected pulmonary embolism undergo computed tomographic (CT ...
L. M. van der Pol   +22 more
semanticscholar   +1 more source

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