Results 81 to 90 of about 130,583 (297)

Tislelizumab: Structural Innovations and Expanding Clinical Horizons in Next‐Generation PD‐1 Immunotherapy

open access: yesChronic Diseases and Translational Medicine, EarlyView.
The interaction of tislelizumab with PD‐1/PD‐L1 in the tumor microenvironment. Tislelizumab targets PD‐1 on T cells, blocking its interaction with PD‐L1 on tumor cells. This action is facilitated by a modified F(ab) region that limits Fc‐γ receptor binding, thereby enhancing the antitumor immune response. ABSTRACT Tislelizumab is a next‐generation PD‐1
Thy T. Nguyen   +4 more
wiley   +1 more source

Safety and Efficacy of the Bimodal Armadillo Catheter for Intracranial Interventions via the Transfemoral Approach

open access: yesStroke: Vascular and Interventional Neurology
Background The Armadillo (Q'Apel Medical Inc., Fremont, CA) is a novel bimodal guide catheter, combining properties of a long support sheath with a large‐bore distal access catheter, whose stiffness can be adjusted from “track” mode during navigation to “
Jeffrey M. Katz   +4 more
doaj   +1 more source

Pulmonary embolism

open access: yesInternational Journal of Critical Illness and Injury Science, 2013
Pulmonary embolism (PE) is responsible for approximately 100,000 to 200,000 deaths in the United States each year. With a diverse range of clinical presentations from asymptomatic to death, diagnosing PE can be challenging. Various resources are available, such as clinical scoring systems, laboratory data, and imaging studies which help guide ...
Tarbox, Abigail K., Swaroop, Mamta
openaire   +3 more sources

Registries on transcatheter edge‐to‐edge repair in heart failure: Current evidence and future perspectives

open access: yesEuropean Journal of Heart Failure, EarlyView.
Clinical evidence in transcatheter edge‐to‐edge valve repair. EF, ejection fraction; eGFR, estimated glomerular filtration rate; EROA, effective regurgitant orifice area; GDMT, guideline‐directed medical therapy; HF, heart failure; HHF, hospitalization for heart failure; LVEDV, left ventricular end‐diastolic volume; MR, mitral regurgitation; MVARC ...
Gianluigi Savarese   +13 more
wiley   +1 more source

Arterial embolism

open access: yesInternational Journal of Critical Illness and Injury Science, 2013
Surgical and intensive care patients are at a heightened risk for arterial embolization due to pre-existing conditions such as age, hypercoagulability, cardiac abnormalities and atherosclerotic disease. Most arterial emboli are clots that originate in the heart and travel to distant vascular beds where they cause arterial occlusion, ischemia, and ...
Lyaker, Michael R.   +4 more
openaire   +3 more sources

Prognostic value of NT‐proBNP in patients with primary mitral regurgitation undergoing transcatheter edge‐to‐edge repair

open access: yesEuropean Journal of Heart Failure, EarlyView.
In the PRIME‐MR study, patients with higher N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) tertiles more frequently reached death or heart failure hospitalization (HFH) within 3 years. Log‐transformed NT‐proBNP levels independently predicted the primary endpoint (adjusted hazard ratio 1.17, 95% confidence interval 1.07–1.28; p < 0.001).
Philipp von Stein   +70 more
wiley   +1 more source

Re-Do Endovascular Endoleak Embolization by Transprosthetic Puncture After Endovascular Aneurysm Repair

open access: yesJACC: Case Reports
Background: Compared with open repair of abdominal aortic aneurysms, endovascular aneurysm repair (EVAR) is less invasive and results in better perioperative outcomes and lower perioperative mortality risk.
Livio D’Angelo, MD   +6 more
doaj   +1 more source

Using Flight Plan for Embolization Technique Based on Carotid Body Tumor Angiography to Improve Surgical Treatment of the Lesion: Report of Two Cases

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Carotid body tumor (CBT) is a rare type of paraganglioma in head and neck region, with a high risk of surgical bleeding and nerve damage. Here we applied a new imaging tool termed “Flight Plan for Embolization” (FPFE) technique to better identify tumors' feeding arteries so that better dissection and bleeding control can be made to ...
Haotian Huanggu   +4 more
wiley   +1 more source

Management of Retropharyngeal Lymph Node Metastases in Thyroid Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Retropharyngeal lymph node (RPLN) metastases in thyroid cancer are rare, with optimal management underreported. Methods Retrospective study of consecutive thyroid cancer patients with RPLN metastases treated at MD Anderson Cancer Center between 2000 and 2024.
Isabelle Fournier   +19 more
wiley   +1 more source

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