Results 1 to 10 of about 6,560,813 (267)

Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy

open access: yesFrontiers in Pharmacology, 2023
Aberrant activity of the cysteine protease Cathepsin S (CTSS) has been implicated across a wide range of pathologies. Notably in cancer, CTSS has been shown to promote tumour progression, primarily through facilitating invasion and migration of tumour ...
P. Smyth   +12 more
doaj   +1 more source

Emerging Insights on Caspases in COVID-19 Pathogenesis, Sequelae, and Directed Therapies

open access: yesFrontiers in Immunology, 2022
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a significant global health emergency with new variants in some cases evading current therapies and approved vaccines.
Thomas A. Premeaux   +7 more
doaj   +1 more source

THERAPEUTICS [PDF]

open access: yesThe American Journal of the Medical Sciences, 1905
n ...
Wilcox, Reynold Webb   +1 more
openaire   +2 more sources

Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy [PDF]

open access: yes, 2020
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, including neurological disorders ...
Capilla González, Vivian   +4 more
core   +1 more source

Novel Ex Vivo Zymography Approach for Assessment of Protease Activity in Tissues with Activatable Antibodies

open access: yesPharmaceutics, 2021
Proteases are involved in the control of numerous physiological processes, and their dysregulation has been identified in a wide range of pathologies, including cancer.
Bruce Howng   +5 more
doaj   +1 more source

THERAPEUTICS [PDF]

open access: yesThe American Journal of The Medical Sciences, 1920
n ...
Lambert, Samuel W., Lieb, Charles C.
openaire   +1 more source

Potential Role of Natural Products to Combat Radiotherapy and Their Future Perspectives

open access: yesMolecules, 2021
Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy (RT) are the common cancer treatments. In addition to these limitations, the development of adverse effects from chemotherapy and RT reduces the quality of life for ...
Rokeya Akter   +8 more
doaj   +1 more source

Pyridine Scaffolds, Phenols and Derivatives of Azo Moiety: Current Therapeutic Perspectives

open access: yesMolecules, 2021
Synthetic heterocyclic compounds have incredible potential against different diseases; pyridines, phenolic compounds and the derivatives of azo moiety have shown excellent antimicrobial, antiviral, antidiabetic, anti-melanogenic, anti-ulcer, anticancer ...
Tehreem Tahir   +6 more
doaj   +1 more source

Therapeutic Potential of Microalgae-Derived Bioactive Metabolites Is Influenced by Different Large-Scale Culture Strategies

open access: yesMarine Drugs, 2022
Microalgae have been identified as one of the most promising sources of novel bioactive compounds for biomedical applications, the food industry, and cosmetics. In the last decade, several biotechnological developments have facilitated the identification
Jezabel Garcia-Parra   +2 more
doaj   +1 more source

Evaluation of Prophylactic and Therapeutic Effects of Silymarin on Phenobar- bital-Induced Hepatotoxicity in Cats [PDF]

open access: yesIranian Journal of Veterinary Medicine, 2020
BACKGROUND: Phenobarbital is one of the most commonly used drugs to treat epilepsy and other seizure disorders in dogs and cats. Hepatotoxicity following phenobarbital administration is dose-dependent.
Bahman Mosallanejad   +3 more
doaj   +1 more source

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