Results 31 to 40 of about 3,237,605 (268)

Precision Breast Cancer Medicine: Early Stage Triple Negative Breast Cancer—A Review of Molecular Characterisation, Therapeutic Targets and Future Trends

Frontiers in Oncology, 2022
Personalised approaches to the management of all solid tumours are increasing rapidly, along with wider accessibility for clinicians. Advances in tumour characterisation and targeted therapies have placed triple-negative breast cancers (TNBC) at the ...
Karen Pinilla, Karen Pinilla, Karen Pinilla, Lynsey M. Drewett, Lynsey M. Drewett, Rebecca Lucey, Rebecca Lucey, Jean E. Abraham, Jean E. Abraham, Jean E. Abraham   +9 more
doaj   +1 more source

In memory of academician V.I. Pokrovsky (04/01/1929 - 10/29/2020)

Терапевтический архив, 2020
In memory of academician V.I. Pokrovsky (04/01/1929 - 10/29/2020)
Collegium of the journal "Therapeutic archive"
doaj  

Plant derived bioactive compounds for the treatment of neurodegeneration and neuroimmune disorders associated with the complement system

Exploration of Immunology
The complement system is a key component of the innate immune system that mediates the clearance of pathogens, apoptotic cells, and cellular debris.
Jeyaparthasarathy Narayanaperumal, Ganesh Gopal   +1 more
doaj   +1 more source

Novel Diagnostics and Therapeutics in Sepsis

Biomedicines, 2021
Sepsis management demands early diagnosis and timely treatment that includes source control, antimicrobial therapy, and resuscitation. Currently employed diagnostic tools are ill-equipped to rapidly diagnose sepsis and isolate the offending pathogen ...
Kieran Leong, Bhavita Gaglani, Ashish K. Khanna, Michael T. McCurdy   +3 more
doaj   +1 more source

Technical success, procedural safety, and efficacy of the Silk Vista Baby in the treatment of cerebral aneurysms over a mid-to-long-term follow-up

Frontiers in Neurology
BackgroundLong-term follow-up of cerebral aneurysms treated with the Silk Vista Baby (SVB) flow diverter is lacking. This study aimed to assess the technical success, procedural safety, and efficacy of the SVB (Balt, Montmorency, France) for the ...
Claudio Rodríguez-Fernández, Pedro Ruiz-Garcia, Maria Jesús Garcia-Sanchez, Martiel Manrique-Zegarra, Carlos Toledano-Illán, Jorge Escartin, Miguel Angel Vences, Miguel Angel Vences, Luis Angel Rubio, Alex Luttich, José Manuel Pumar   +10 more
doaj   +1 more source

Salmonella enterica isolated from selected poultry farms in Kwara State, Nigeria between 2015 and 2016 showed resistance to critical antimicrobials [PDF]

Journal of Central European Agriculture, 2020
Salmonellosis is a major public health hazard globally. This study was designed to determine the antimicrobial resistance among Salmonella serovars isolated from selected poultry farms in Kwara State, Nigeria between 2015 and 2016 using a cross sectional
Akeem Ahmed, Moshood Raji, Paul Mamman, Clara Kwanashie, Ibrahim Raufu, Ganiu Akorede, Abdulfatai Aremu, Khalid Biobaku, Yusuf Suleiman   +8 more
doaj   +1 more source

Metabolomics: A New Era in the Diagnosis or Prognosis of B-Cell Non-Hodgkin’s Lymphoma

Diagnostics, 2023
A wide range of histological as well as clinical properties are exhibited by B-cell non-Hodgkin’s lymphomas. These properties could make the diagnostics process complicated.
Abdullah Alfaifi, Mohammed Y. Refai, Mohammed Alsaadi, Salem Bahashwan, Hafiz Malhan, Waiel Al-Kahiry, Enas Dammag, Ageel Ageel, Amjed Mahzary, Raed Albiheyri, Hussein Almehdar, Ishtiaq Qadri   +11 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Design and screening of novel endosomal escape compounds that enhance functional delivery of oligonucleotides in vitro

Molecular Therapy: Nucleic Acids
Antisense oligonucleotides (ASOs), including splice-switching oligonucleotides (SSOs), are promising therapeutic approaches for targeting genetic defects.
H. Yesid Estupiñán, Tom Baladi, Samantha Roudi, Michael J. Munson, Jeremy Bost, Oskar Gustafsson, Daniel Velásquez-Ramírez, Deepak Kumar Bhatt, Daniel Hagey, Dennis Hekman, Shalini Andersson, Samir EL Andaloussi, Anders Dahlén   +12 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source