Results 51 to 60 of about 6,560,912 (366)

Mechanism of bisphosphonate-related osteonecrosis of the jaw (BRONJ) revealed by targeted removal of legacy bisphosphonate from jawbone using competing inert hydroxymethylene diphosphonate

eLife, 2022
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) presents as a morbid jawbone lesion in patients exposed to a nitrogen-containing bisphosphonate (N-BP). Although it is rare, BRONJ has caused apprehension among patients and healthcare providers and
Hiroko Okawa, Takeru Kondo, Akishige Hokugo, Philip Cherian, Jesus J Campagna, Nicholas A Lentini, Eric C Sung, Samantha Chiang, Yi-Ling Lin, Frank H Ebetino, Varghese John, Shuting Sun, Charles E McKenna, Ichiro Nishimura   +13 more
doaj   +1 more source

Dexamethasone for Chemotherapy‐Induced Nausea and Vomiting Prevention in Pediatric Patients: International Consensus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An international Delphi panel of experts developed consensus statements to delineate the circumstances where the risks of dexamethasone as an antiemetic do and do not outweigh its benefits. Procedure Experts in supportive care of pediatric patients were invited to participate.
Negar Shavandi, Paula D. Robinson, Shana Jacobs, L. Lee Dupuis, the International Pediatric Dexamethasone Panel, Sameer Bakhshi, Tiene Bauters, Eva Brack, Simone Cesaro, Claire Fosbrook, Jason Freedman, Tamara MacDonald, Eloise Neumann, Venkatraman Radhakrishnan, Rod Rassekh, Florian Slimano, Johnathan Soggee, Joel Thompson, Marianne van de Wetering, Milena Villarroel, Jasper Wong   +20 more
wiley   +1 more source

Processing the Therapeutic Relationship [PDF]

, 2009
The authors propose that if therapists and clients process their therapeutic relationship (i.e., directly address in the here and now feelings about each other and about the inevitable problems that emerge in the therapy relationship), feelings will be ...
Hill, Clara E, Knox, Sarah
core   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Gelatin Sponge Particle Embolization of Spontaneously Ruptured Intrahepatic Arterial Aneurysms in a Patient with Polyarteritis Nodosa: A Case Report

대한영상의학회지, 2017
Multiple intrahepatic arterial aneurysms and spontaneous aneurysmal rupture associated with polyarteritis nodosa leading to hemoperitoneum are extremely rare occurrences, but the conditions can be life-threatening if left untreated because of the risk of
Myung Jin Seol, Kyung Hee Noh, Young Jun Kim, Doo Sung Jeon   +3 more
doaj   +1 more source

Blockade of LAG-3 Immune Checkpoint Combined With Therapeutic Vaccination Restore the Function of Tissue-Resident Anti-viral CD8+ T Cells and Protect Against Recurrent Ocular Herpes Simplex Infection and Disease

Frontiers in Immunology, 2018
Recurrent viral diseases often occur after the viruses evade the hosts' immune system, by inducing exhaustion of antiviral T cells. In the present study, we found that functionally exhausted herpes simplex virus type 1 (HSV-1) -specific CD8+ T cells ...
Soumyabrata Roy, Pierre-Grégoire Coulon, Ruchi Srivastava, Hawa Vahed, Grace J. Kim, Sager S. Walia, Taikun Yamada, Mona A. Fouladi, Vincent T. Ly, Lbachir BenMohamed, Lbachir BenMohamed, Lbachir BenMohamed   +11 more
doaj   +1 more source

Targeting matrix metalloproteases: A promising strategy for herbal medicines to treat rheumatoid arthritis

Frontiers in Immunology, 2022
As a type of metalloproteinase, matrix metalloproteinases (MMPs) can be divided into collagenase, gelatinase, stromelysins, membrane-type (MT)-MMPs and heterogeneous subgroups according to their structure and function.
Ruo-Lan Li, Hu-Xinyue Duan, Qi Liang, Yong-Liang Huang, Ling-Yu Wang, Qing Zhang, Chun-Jie Wu, Shu-Qin Liu, Wei Peng   +8 more
doaj   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

From Poison to Promise: The Evolution of Tetrodotoxin and Its Potential as a Therapeutic

Toxins, 2021
Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria.
Gary M. Bucciarelli, Maren Lechner, Audrey Fontes, Lee B. Kats, Heather L. Eisthen, H. Bradley Shaffer   +5 more
doaj   +1 more source

Studi Fenomenologi: Pengalaman Perawat Menerapkan Komunikasi Terapeutik Mengatasi Dampak Hospitalisasi Pada Anak Pra Sekolah Di Ruang Clara Charitas Hospital Km.7 Palembang [PDF]

, 2019
Background: the number of hospitalized Chlidren in hospitals is still high, in 2015 as many as 2,78% of children in Indonesia were hospitalized, while the impact of hospitalizaton was un avoiddable.
Wahyusari, Dian
core