Results 11 to 20 of about 15,382 (204)

Dim Light at Night Promotes Circadian Disruption in Female Rats, at the Metabolic, Reproductive, and Behavioral Level

Advanced Biology, Volume 7, Issue 11, November 2023., 2023
Experimental rats are exposed to dim light at night (DLAN) and are compared to rats exposed to a light–dark cycle. After 5 weeks, DLAN rats exhibit disrupted circadian rhythms in temperature and activity, impaired metabolism, persistent estrous, and depressive‐like behavior.
Mariana Gutiérrez‐Pérez, Shellye González‐González, Karla P. Estrada‐Rodriguez, Estefania Espítia‐Bautista, Mara A. Guzmán‐Ruiz, Rene Escalona, Carolina Escobar, Natalí N. Guerrero‐Vargas   +7 more
wiley   +1 more source

Anatomía microscópica normal de la glándula tiroides. Principios básicos para el residente de Endocrinología y anatomía patológica con una breve nota histórica

Revista Colombiana de Endocrinología, Diabetes y Metabolismo, 2022
Contexto: es necesario conocer las características histológicas normales de la glándula tiroides para comprender los procesos patológicos de esta glándula.
Andrea Heredia-Jara, Carlos Ortiz-Hidalgo   +1 more
doaj   +1 more source

Quantitative analysis of parent‐of‐origin effect in reproductive and morphological selection criteria in the Pura Raza Española horse

Journal of Animal Breeding and Genetics, Volume 140, Issue 6, Page 596-606, November 2023., 2023
Abstract It is generally assumed that parents make a genetically equal contribution to their offspring, but this assumption might not always hold. This is because the expression of a gene can be blocked by methylation during gametogenesis, and the degree of methylation can depend on the origin of the parental gene (imprinting) or by preferential ...
Davinia I. Perdomo‐González, Luis Varona, Antonio Molina, Nora Laseca, Mercedes Valera   +4 more
wiley   +1 more source

SOD1 Astrocyte-Derived Extracellular Vesicles Induce Motor Neuron Death by a miRNA-155-5p-Mediated Mechanism

ASN Neuro, 2023
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by upper and lower motor neuron (MN) degeneration. Astrocytes surrounding MNs are known to modulate ALS progression. When cocultured with astrocytes overexpressing the
Soledad Marton, Ernesto Miquel, Joaquín Acosta-Rodríguez, Santiago Fontenla, Gabriela Libisch, Patricia Cassina   +5 more
doaj   +1 more source

Extracellular vesicles from human plasma dampen inflammation and promote tissue repair functions in macrophages

Journal of Extracellular Vesicles, Volume 12, Issue 6, June 2023., 2023
Abstract Although inflammation is a vital defence response to infection, if left uncontrolled, it can lead to pathology. Macrophages are critical players both in driving the inflammatory response and in the subsequent events required for restoring tissue homeostasis.
Alan M. Adamczyk, María Luz Leicaj, Martina Paula Fabiano, Gonzalo Cabrerizo, Nadia Bannoud, Diego O. Croci, Kenneth W. Witwer, Federico Remes Lenicov, Matías Ostrowski, Paula Soledad Pérez   +9 more
wiley   +1 more source

The orobasal organ (of Ackerknecht): A bizarre structure of the mammalian oral cavity

Journal of Morphology, Volume 284, Issue 6, June 2023., 2023
In 1912, Ackerknecht discovered and described an epithelial invagination behind the lower medial incisors in different mammalian species. This rudimentary structure might be a vestiagial organ which lost its physiological function. Named after its discoverer the “orobasal organ of Ackerknecht” is widely unknown in the scientific world.
Moritz Stäber, Silke D. Storsberg, Sven Schumann   +2 more
wiley   +1 more source

A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]

, 2017
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel, Delgui, Laura Ruth   +1 more
core   +5 more sources

Hernia paracecal, reto diagnóstico y quirúrgico: reporte de caso y revisión de la literatura

Revista Colombiana de Cirugía, 2020
Introducción. La hernia paracecal es una entidad rara que corresponde al 13 % de todas las hernias internas. Aunque algunas pueden ser adquiridas, la mayoría son congénitas y se originan en los recesos creados durante la adherencia y fusión de los ...
Carolina María Rodríguez Vargas, Eduardo Francisco Bayter Mendoza, Rogers Leonardo Baquero García   +2 more
doaj   +1 more source

Deciphering opening mechanisms of 14-3-3 proteins. [PDF]

Protein Sci
Abstract The 14‐3‐3 proteins are a highly conserved family of regulatory molecules that play crucial roles in various cellular processes. They are known for their ability to bind to phosphorylated serine and threonine residues on target proteins, which allows them to modulate their activity, localization, and stability.
Barrera EE, Skrabana R, Bustos DM.
europepmc   +2 more sources

Rescue of neurogenesis and age‐associated cognitive decline in SAMP8 mouse: Role of transforming growth factor‐alpha

Aging Cell, Volume 22, Issue 6, June 2023., 2023
Diterpene ER272 rescues of adult hippocampal neurogenesis and cognitive performance in the aging brain. Abstract Neuropathological aging is associated with memory impairment and cognitive decline, affecting several brain areas including the neurogenic niche of the dentate gyrus of the hippocampus (DG).
Ricardo Gómez‐Oliva, Sergio Martínez‐Ortega, Isabel Atienza‐Navarro, Samuel Domínguez‐García, Carlos Bernal‐Utrera, Noelia Geribaldi‐Doldán, Cristina Verástegui, Abdellah Ezzanad, Rosario Hernández‐Galán, Pedro Nunez‐Abades, Monica Garcia‐Alloza, Carmen Castro   +11 more
wiley   +1 more source