Building Principles for Constructing a Mammalian Blastocyst Embryo
The self-organisation of a fertilised egg to form a blastocyst structure, which consists of three distinct cell lineages (trophoblast, epiblast and hypoblast) arranged around an off-centre cavity, is unique to mammals.
Peter L. Pfeffer
doaj +1 more source
Terrestrial Planets Formation around Circumbinary Habitable Zone: Inward Migration in the Planetesimal Swarm [PDF]
According to the core accretion theory, circumbinary embryos can form only beyond a critical semimajor axis (CSMA). However, due to the relatively high density of solid materials in the inner disk, significant amount of small planetesimals must exist in the inner zone when embryos were forming outside this CSMA.
arxiv +1 more source
Embryo metabolism : what does it really mean? [PDF]
The study of early embryo metabolism has fascinated researchers in the field for nearly a century. Herein, we give a brief account of the general features of embryo metabolism and some consideration of the research performed to reach such conclusions. It
Lewis, Niamh, Sturmey, Roger
core
Cilia, calcium and the basis of left-right asymmetry
The clockwise rotation of cilia in the developing mammalian embryo drives a leftward flow of liquid; this genetically regulated biophysical force specifies left-right asymmetry of the mammalian body.
Norris Dominic P
doaj +1 more source
The growth of planetary embryos: orderly, runaway, or oligarchic? [PDF]
We consider the growth of a protoplanetary embryo embedded in a planetesimal disk. We take into account the dynamical evolution of the disk caused by (1) planetesimal-planetesimal interactions, which increase random motions and smooth gradients in the disk, and (2) gravitational scattering of planetesimals by the embryo, which tends to heat up the disk
arxiv +1 more source
Lack of RNA-DNA oligonucleotide (chimeraplast) mutagenic activity in mouse embryos [PDF]
There are numerous reports of the use of RNA-DNA oligonucleoticles (chimeraplasts) to correct point mutations in vitro and in vivo, including the human apolipoprotein E gene (ApoE).
Owen, JS, Simons, JP, Tagalakis, AD
core +1 more source
The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking [PDF]
Breaking embryonic symmetry is an essential prerequisite to shape the initially symmetric embryo into a highly organized body plan that serves as the blueprint of the adult organism.
Cornwall-Scoones, Jake+2 more
core
Repeats as global DNA methylation marker in bovine preimplantation embryos [PDF]
DNA methylation undergoes dynamic changes and is a crucial part of the epigenetic regulation during mammalian early development. To determine the DNA methylation levels in bovine embryos, we applied a bisulfite sequencing based method aimed at repetitive
Li, Wenwen, Peelman, Luc, Van Soom, Ann
core +2 more sources
Endogenous retroviruses (ERVs) are repetitive sequences in the genome, belonging to the retrotransposon family. During the course of life, ERVs are associated with multiple aspects of chromatin and transcriptional regulation in development and ...
Yangquan Xiang, Hongqing Liang
doaj +1 more source
EmbryosFormer: Deformable Transformer and Collaborative Encoding-Decoding for Embryos Stage Development Classification [PDF]
The timing of cell divisions in early embryos during the In-Vitro Fertilization (IVF) process is a key predictor of embryo viability. However, observing cell divisions in Time-Lapse Monitoring (TLM) is a time-consuming process and highly depends on experts.
arxiv