Results 1 to 10 of about 10,920 (124)
Live imaging of whole mouse embryos during gastrulation: migration analyses of epiblast and mesodermal cells. [PDF]
PLoS ONE, 2013 During gastrulation in the mouse embryo, dynamic cell movements including epiblast invagination and mesodermal layer expansion lead to the establishment of the three-layered body plan.
Takehiko Ichikawa +6 more
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Suppressing Nodal Signaling Activity Predisposes Ectodermal Differentiation of Epiblast Stem Cells
Stem Cell Reports, 2018 Summary: The molecular mechanism underpinning the specification of the ectoderm, a transient germ-layer tissue, during mouse gastrulation was examined here in a stem cell-based model.
Zhisong He +2 more
exaly +3 more sources
Cell Reports, 2016 Mouse embryonic stem cells (ESCs) and the inner cell mass (ICM)-derived epiblast exhibit naive pluripotency. ESC-derived epiblast stem cells (EpiSCs) and the postimplantation epiblast exhibit primed pluripotency.
Dario Acampora +2 more
exaly +3 more sources
The number of primitive endoderm cells in the inner cell mass is regulated by platelet-derived growth factor signaling in porcine preimplantation embryos [PDF]
Animal Bioscience, 2023 Objective Discovering the mechanism of cell specification is important to manipulate cellular lineages. To obtain lineage-specific cell lines, the target lineage needs to be promoted, and counterpart lineages should be suppressed.
Jong-Nam Oh +7 more
doaj +1 more source
The Long Terminal Repeats of ERV6 Are Activated in Pre-Implantation Embryos of Cynomolgus Monkey
Cells, 2021 Precise gene regulation is critical during embryo development. Long terminal repeat elements (LTRs) of endogenous retroviruses (ERVs) are dynamically expressed in blastocysts of mammalian embryos.
Kui Duan +8 more
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Capturing Pluripotency and Beyond
Cells, 2021 During the development of a multicellular organism, the specification of different cell lineages originates in a small group of pluripotent cells, the epiblasts, formed in the preimplantation embryo.
Chih-Yu Yeh +3 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2022 Live imaging of migrating and interacting cells in developing embryos has opened a new means for deciphering fundamental principles in morphogenesis and patterning, which was not possible with classic approaches of experimental embryology.
Koya Yoshihi +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 Embryonic stem cell (ESC) derivation from single blastomeres of 8-cell mouse embryos results in lower derivation rates than that from whole blastocysts, raising a biological question about the developmental potential of sister blastomeres.
Sandra Alonso-Alonso +9 more
doaj +1 more source
Cell Reports, 2021 Summary: At implantation, the embryo establishes contacts with the maternal endometrium. This stage is associated with a high incidence of preclinical pregnancy losses. While the maternal factors underlying uterine receptivity have been investigated, the
Matteo Amitaba Molè +5 more
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Frontiers in Cell and Developmental Biology, 2021 From fertilization to onset of gastrulation, a mammalian embryo goes through several rounds of cellular morphogenesis resembling phenomena of epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET), collectively referred to as
Galym Ismagulov +2 more
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