Advanced Management of Severe Adenomyosis in IVF: A Personalized Approach With Extended GnRH Agonist and Letrozole Therapy. [PDF]
Fatemi C +5 more
europepmc +1 more source
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Editorial: Cellular micro-environment of the endometrium: reproduction, embryo implantation, and placentation - from bench to bedside and beyond to tissue engineering. [PDF]
Varga I, Carriel V.
europepmc +1 more source
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source
Impact of three-month tuberculosis preventive treatment (3HP) on IVF-ET outcomes in infertile women with tuberculosis infection: a retrospective before-after study. [PDF]
Li J +7 more
europepmc +1 more source
Astrocyte Enrichment of 3D Cortical Constructs Enhances Brain Repair
This study highlights the role of astrocytes in supporting neural progenitor cell survival and differentiation after traumatic brain injury. Astrocytes enhanced neuronal differentiation, improved cell survival in co‐cultures, and promoted integration of microfluidics‐based implants with host tissue following implantation. Additionally, increased axonal
Elisa M. Cruz +20 more
wiley +1 more source
Effects of Sperm DNA Fragmentation on Embryonic Cleavage and Semen Parameters in In Vitro Fertilization Treatment. [PDF]
Chuang YL +6 more
europepmc +1 more source
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li +11 more
wiley +1 more source
Impact of serum progesterone levels and rescue progesterone supplemental luteal support on pregnancy outcomes in frozen embryo transfer: a controlled trial. [PDF]
Azizi Kutenaee M +5 more
europepmc +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source

