Results 241 to 250 of about 547,146 (311)

Anti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery

Advanced Science, EarlyView.
Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...
Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu   +14 more
wiley   +1 more source

Haptoglobin as a supplement in in vitro embryo culture: a tool for improving bovine embryo development and quality. [PDF]

Biol Res
Cañón-Beltrán K, Cajas YN, Martínez-López C, Moros-Nicolás C, Sòria-Monzó P, Balastegui-Alarcón M, Avilés M, Rizos D, García-Vázquez FA, Izquierdo-Rico MJ.   +9 more
europepmc   +1 more source

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

Advanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li, Yuxin Wu, Shuai Zhou, Peipei Tang, Jiaming Wei, Ling Liu, Zhenyi Wang, Deyang Shi, Shengnan Yuan, Qingyu Zhang, Shihui Wang, Qing Zhang, Huan Zhao, Rui Zhang, Yingying Wang, Shiwei Yang, Xiangli Chen, Xiaojing Shi, Guangzhi Liu, Yuwei Zhang, Jinming Li, Xu Dong Zhang, Rick F Thorne, Dongping Wei, Zumin Zhu, Song Chen   +25 more
wiley   +1 more source

Chick embryo development assessment and fertility detection using pixel-wise hyperspectral image analysis and deep learning. [PDF]

Poult Sci
Ghaderi M, Mireei SA, Masoumi A, Sedghi M, Nazeri M.   +4 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Genomic-Encoded Mitovirus RdRp Is Required for Embryo Development and Maintaining Mitochondrial Dynamics in <i>Arabidopsis</i>. [PDF]

Int J Mol Sci
Gong Y, Chen R, Yang C, Lu Y, Fu Z, Feng Y, Li X, Li L, Li X.   +8 more
europepmc   +1 more source

Effects of hormone-primed oviduct epithelial cell co-culture system on swine SCNT embryo development. [PDF]

Front Cell Dev Biol
Chen ZP, Wang J, Bian CD, Wang DY, Feng DH, Wei MY, Yu DW, Sun WJ, Zhang LL.   +8 more
europepmc   +1 more source

The hierarchical folding dynamics of topologically associating domains during early embryo development. [PDF]

BMC Biol
Bai X, Tang X, Wang Y, Yue S, Xu X, Hu P, Xu J, Li Y, Wang J, Tao H, Zheng Y, Chen B, Tian M, Lin L, Wang R, Sun Y, Ren C, Bo X, Li H, Chen H, Lu M.   +20 more
europepmc   +1 more source

Regulation of autophagy and its role in late preimplantation during mouse embryo development. [PDF]

Sci Rep
Uechi K, Koide I, Kanie S, Yamazaki T, Kishigami S.   +4 more
europepmc   +1 more source

Teratozoospermia and Embryo Development: The Significance of Sperm Selection in In Vitro Fertilization Success. [PDF]

J Clin Med
Naghi P, Zaha IA, Stefan L, Sorian A, Marcu A, Sachelarie L, Huniadi A.   +6 more
europepmc   +1 more source