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Programming of Embryonic Development [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
Assisted reproductive techniques (ART) and parental nutritional status have profound effects on embryonic/fetal and placental development, which are probably mediated via “programming” of gene expression, as reflected by changes in their epigenetic landscape. Such epigenetic changes may underlie programming of growth, development, and function of fetal
Carl R. Dahlen   +7 more
openaire   +2 more sources

Retinoids in Embryonic Development [PDF]

open access: yesBiomolecules, 2020
Retinoids constitute a class of compounds chemically related to vitamin A [...]
Schubert, Michael, Gibert, Yann
openaire   +3 more sources

Waves in Embryonic Development

open access: yesAnnual Review of Biophysics, 2022
Embryonic development hinges on effective coordination of molecular events across space and time. Waves have recently emerged as constituting an ubiquitous mechanism that ensures rapid spreading of regulatory signals across embryos, as well as reliable control of their patterning, namely, for the emergence of body plan structures.
Di Talia, Stefano, Vergassola, Massimo
openaire   +2 more sources

NF-κB activation impedes the transdifferentiation of hypertrophic chondrocytes at the growth plate of mouse embryos in diabetic pregnancy

open access: yesJournal of Orthopaedic Translation, 2021
Background: Diabetes mellitus could cause numerous complications and health problems including abnormality of endochondral bone formation during embryogenesis. However, the underlying mechanisms still remain obscure.
Xi Liu   +9 more
doaj   +1 more source

CXCL5 Downregulation in Villous Tissue Is Correlated With Recurrent Spontaneous Abortion

open access: yesFrontiers in Immunology, 2021
Recurrent spontaneous abortion (RSA) affects 5% of childbearing-age women worldwide. Inadequate trophoblast invasion is one of the main reasons for the development of RSA; however, the underlying molecular mechanisms for RSA have not been fully ...
Sainan Zhang   +5 more
doaj   +1 more source

USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN

open access: yesFrontiers in Cell and Developmental Biology, 2021
Background: Polycystic ovarian syndrome (PCOS) is an endocrine-related disease related to abnormal folliculogenesis and is a leading cause of infertility worldwide.
Yue Gao   +5 more
doaj   +1 more source

FoxO1 in embryonic development [PDF]

open access: yesTranscription, 2012
Establishment of the maternal-fetal circulation during embryonic development is a fundamental process required for effective exchange of nutrients, waste products and signaling factors critical to all subsequent stages of fetal growth and development.
Anwarul, Ferdous, Joseph A, Hill
openaire   +2 more sources

Mitochondrial contributions to oocyte and embryonic quality in bovine [PDF]

open access: yesSPERMOVA, 2017
Mitochondria are powerhouse organelles involved in several vital functions in cells, mainly maintaining balance between ATP synthesis and oxidative stress during early development in mammalian embryos.
Baldoceda L, Robert C
doaj   +1 more source

Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors

open access: yesFrontiers in Cell and Developmental Biology, 2021
Whether or not the process of somitogenesis and myogenesis is affected by excessive caffeine intake still remains ambiguous. In this study, we first showed that caffeine treatment results in chest wall deformities and simultaneously reduced mRNA ...
Nian Wu   +12 more
doaj   +1 more source

Retinoids in Embryonal Development [PDF]

open access: yesPhysiological Reviews, 2000
The key role of vitamin A in embryonal development is reviewed. Special emphasis is given to the physiological action of retinoids, as evident from the retinoid ligand knockout models. Retinoid metabolism in embryonic tissues and teratogenic consequences of retinoid administration at high doses are presented.
S A, Ross   +3 more
openaire   +2 more sources

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