Results 1 to 10 of about 173,484 (139)

Alternative Developmental Toxicity Screening Methods Using Chick Embryo-Based Models. [PDF]

J Appl Toxicol
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Kim JH, Park C, Kim D, Jeong W, Lee J.
europepmc   +2 more sources

A short-term chick embryo in vivo xenograft model to study retinoblastoma cancer stem cells

Indian Journal of Ophthalmology, 2022
Purpose: Cancer stem cells (CSCs) reported in various tumors play a crucial role in tumorigenesis and metastasis of retinoblastoma (Rb). Following the efforts to reduce, replace, and refine the use of mammalian models, we aimed to establish a short-term ...
Rohini M Nair, Narayana V L Revu, Sucharita Gali, Prathap Reddy Kallamadi, Varsha Prabhu, Radhika Manukonda, Harishankar Nemani, Swathi Kaliki, Geeta K Vemuganti   +8 more
doaj   +1 more source

The first non-mammalian synapsid embryo from the Triassic of South Africa

PLoS ONE
Oviparity was likely the plesiomorphic reproductive condition for non-mammalian Synapsida, the stem-mammal group. Yet, despite nearly two centuries of research, no definitive fossil eggs of late Palaeozoic or early Mesozoic synapsids have been discovered.
Julien Benoit, Vincent Fernandez, Jennifer Botha   +2 more
doaj   +2 more sources

Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases

Molecular Imaging, 2018
Metastasis is the most common cause of death for patients with cancer. To fully understand the steps involved in metastatic dissemination, in vivo models are required, of which murine ones are the most common.
Anne Herrmann PhD, Arthur Taylor PhD, Patricia Murray PhD, Harish Poptani PhD, Violaine Sée PhD   +4 more
doaj   +1 more source

<i>Lhx9</i> specifically modulates phalanx number, whereas <i>Lhx2</i> constrains digit length in tetrapods. [PDF]

Proc Natl Acad Sci U S A
Tang Y, Bai S, Li S, Mao Y, Dang W, Xue H, Shang S, Jia Z, Li X, Liu Y, Xu X, Irwin DM, Zhang J, Zhang S, Wang Z.   +14 more
europepmc   +1 more source

Stage-Specific Tulane Virus Replication in Zebrafish: Permissive in Embryos, Restricted in Larvae. [PDF]

Food Environ Virol
Chandran S, Gibson KE.
europepmc   +1 more source

First Record of Morphological Abnormalities in an Embryo of the Longtail Stingray (Hypanus longus) From the Ecuadorian Pacific. [PDF]

J Fish Dis
Mera C, Suárez-Aguilar N, Mejía D, Briones-Mendoza J, Carrera-Fernández M.   +4 more
europepmc   +1 more source

Embryonic Torsion and Axial Rotation in Developing Amniotes: Pattern Distribution, Functional Aspects, and Evolutionary Significance. [PDF]

Evol Dev
Blackburn DG, Bonneau LJ.
europepmc   +1 more source

Downstream of β-catenin: A positive feedback loop between Goosecoid and Nodals in Spemann's organizer. [PDF]

Proc Natl Acad Sci U S A
Azbazdar Y, De Robertis EM.
europepmc   +1 more source

Embryotoxicity and Cardiotoxicity Assessment of Chemical Compounds Using Eggs of Lymnaea stagnalis. [PDF]

Curr Protoc
Maddila KSM, Korikani M, Ansari R, Fatima R, Kemphu P, Kancha RK.   +5 more
europepmc   +1 more source