A short-term chick embryo in vivo xenograft model to study retinoblastoma cancer stem cells
Purpose: Cancer stem cells (CSCs) reported in various tumors play a crucial role in tumorigenesis and metastasis of retinoblastoma (Rb). Following the efforts to reduce, replace, and refine the use of mammalian models, we aimed to establish a short-term ...
Rohini M Nair +8 more
doaj +1 more source
Digital Three-Dimensional Atlas of Quail Development Using High-Resolution MRI [PDF]
We present an archetypal set of three-dimensional digital atlases of the quail embryo based on microscopic magnetic resonance imaging (µMRI). The atlases are composed of three modules: (1) images of fixed ex ovo quail, ranging in age from embryonic day 5
Fraser, Scott E. +6 more
core +3 more sources
Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish. [PDF]
In laboratory strains of zebrafish, sex determination occurs in the absence of a typical sex chromosome and it is not known what regulates the proportion of animals that develop as males or females.
Bruce W. Draper +8 more
core +1 more source
MELK-a conserved kinase: functions, signaling, cancer, and controversy. [PDF]
Maternal embryonic leucine zipper kinase (MELK) is a highly conserved serine/threonine kinase initially found to be expressed in a wide range of early embryonic cellular stages, and as a result has been implicated in embryogenesis and cell cycle control.
Beullens, Monique +5 more
core +2 more sources
The first non-mammalian synapsid embryo from the Triassic of South Africa.
Oviparity was likely the plesiomorphic reproductive condition for non-mammalian Synapsida, the stem-mammal group. Yet, despite nearly two centuries of research, no definitive fossil eggs of late Palaeozoic or early Mesozoic synapsids have been discovered.
Julien Benoit +2 more
doaj +2 more sources
Selenoprotein gene nomenclature [PDF]
The human genome contains 25 genes coding for selenocysteine-containing proteins (selenoproteins). These proteins are involved in a variety of functions, most notably redox homeostasis.
Arn\ue9r, Elias S. +52 more
core +3 more sources
Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases
Metastasis is the most common cause of death for patients with cancer. To fully understand the steps involved in metastatic dissemination, in vivo models are required, of which murine ones are the most common.
Anne Herrmann PhD +4 more
doaj +1 more source
Nucleoside diphosphate kinase B is required for the formation of heterotrimeric G protein containing caveolae. [PDF]
Caveolae are flask-shaped invaginations in the plasma membrane that serve to compartmentalize and organize signal transduction processes, including signals mediated by G protein-coupled receptors and heterotrimeric G proteins.
H.A. Katus +8 more
core +4 more sources
Nel positively regulates the genesis of retinal ganglion cells by promoting their differentiation and survival during development [PDF]
Peer reviewedPublisher ...
Adams JC +67 more
core +1 more source
Light Activation of the Phosphoinositide Cycle in Intrinsically Photosensitive Chicken Retinal Ganglion Cells [PDF]
Purpose: In vertebrates, intrinsically photosensitive retinal ganglion cells (ipRGCs) acting as nonvisual photoreceptors transmit environmental illumination information to the brain, regulating diverse non–image-forming tasks.
Contin, Maria Ana +5 more
core +1 more source

