Results 11 to 20 of about 9,662 (120)

The vitellogenin genes in Cynops orientalis: New insights on the evolution of the vtg gene family in amphibians [PDF]

, 2021
The vitellogenins (Vtgs) are glycolipophosphoproteins that play a key role in constituting nutritional reserves for embryo development in nonmammalian vertebrates. However, additional functional roles have been evidenced.
Biscotti M. A., Barucca M., Carducci F., Canapa A.   +3 more
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Single choroideremia Gene in Nonmammalian Vertebrates Explains Early Embryonic Lethality of the Zebrafish Model of Choroideremia [PDF]

, 2009
PURPOSE. Mutations of the CHM gene underlie the X-linked chorioretinal degeneration choroideremia (CHM). The affected gene product, Rab Escort Protein (REP) 1, mediates the post-translational prenyl modification of Rab GTPases.
Gregory-Evans, C Y, Moosajee , M, Pereira-Leal, José B., Seabra, Miguel C, Tulloch , M, Baron, Rudi A, C Seabra, Miguel   +6 more
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New Mediators in the Biology of the Ductus Arteriosus: Lessons from the Chicken Embryo

, 2020
The chicken embryo is an ideal model for the study of new hypotheses on the developmental biology of ductus arteriosus (DA). A unique characteristic of chicken DA is that it is the result of the fusion of two vessels with different embryological origins,
Mohammed, Riazudin, Riazudin Mohammed, Villamor, Eduardo, Saskia van der Sterren, Eduardo Villamor, van der Sterren, Saskia   +5 more
core   +1 more source

Mammalian Oocytes Store mRNAs in a Mitochondria-Associated Membraneless Compartment

, 2023
During the final stages of oocyte growth, transcription ceases only to resume following fertilization. During this cessation, the oocyte and the embryo can only use stores mRNAs to synthesize new products, meaning the storage of maternal mRNAs is ...
Shiya Cheng, Alexandra Stützer, Henning Urlaub, So, Chun, Penir, Sarah, Katarina Harasimov, Cheng, S., Kay Elder, Harasimov, Katarina, Ruhwedel, Torben, Torben Ruhwedel, Stützer, Alexandra, Altmeppen, G., Sarah Penir, Möbius, W., Gerrit Altmeppen, Wiebke Möbius, Melina Schuh, Cheng, Shiya, Luisa M. Welp, Harasimov, K., Altmeppen, Gerrit, Katerina Menelaou, Chun So, Menelaou, K., Blayney, M., Welp, Luisa M., So, C., Welp, L., Schuh, M. ; https://orcid.org/, Urlaub, H., Stützer, A., Menelaou, Katerina, Ruhwedel, T., Schuh, Melina, Elder, K., Martyn Blayney, Blayney, Martyn, Penir, S.   +38 more
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Cytokines in mammalian reproduction and speculation about their possible involvement in nonmammalian viviparity

, 1997
In recent years, the secretion of immunoregulatory factors (cytokines) at the maternofetal interface in mammals has been widely documented. Although cytokine production seems to be a specific phenomenon in mammalian reproduction, the specific roles of ...
RICCI, L.
core   +1 more source

Formation of Distinct Cell Types in the Mouse Blastocyst

, 2012
Early development of the mouse comprises a sequence of cell fate decisions in which cells are guided along a pathway of restricted potential and increasing specialisation.
Morris, Samantha A., Magdalena Zernicka-Goetz, Samantha A. Morris, Zernicka-Goetz, Magdalena   +3 more
core   +1 more source

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Environmental Toxicology and Chemistry, EarlyView.
Abstract There is increasing concern regarding pollutants disrupting the vertebrate thyroid hormone (TH) system, which is crucial for development. Thus, identification of TH system–disrupting chemicals (THSDCs) is an important requirement in the Organisation for Economic Co‐operation and Development (OECD) testing framework.
Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann   +9 more
wiley   +1 more source

Effects of the peroxisome proliferator di(2-ethylhexyl)phthalate on cell turnover and peroxisome proliferation in primary chick embryo hepatocytes

, 2012
The peroxisome proliferator (PP) di(2-ethylhexyl)phthalate (DEHP) is widely used as a plasticizer and can contaminate air, water, and soil. As yet, no data have been published on its potential to induce changes in cell growth of nonmammalian hepatocytes.
E. Arias, Elio Arias
core   +1 more source

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

Journal of Applied Toxicology, EarlyView.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim, Cheoljin Park, Donghee Kim, Wonjun Jeong, Jinsoo Lee   +4 more
wiley   +1 more source

Evolutionary origin and phylogenetic analysis of the novel oocyte-specific eukaryotic translation initiation factor 4E in Tetrapoda.

, 2009
The transcriptionally active, growing oocyte accumulates mRNAs essential for early stages of development, the oocyte-to-embryo transition, in a stable, dormant form.
Marin, de Evsikova, Evsikov, A V
core   +1 more source