Alternative Developmental Toxicity Screening Methods Using Chick Embryo-Based Models. [PDF]
J Appl ToxicolABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Kim JH, Park C, Kim D, Jeong W, Lee J.
europepmc +2 more sources
A short-term chick embryo in vivo xenograft model to study retinoblastoma cancer stem cells
Indian Journal of Ophthalmology, 2022 Purpose: Cancer stem cells (CSCs) reported in various tumors play a crucial role in tumorigenesis and metastasis of retinoblastoma (Rb). Following the efforts to reduce, replace, and refine the use of mammalian models, we aimed to establish a short-term ...
Rohini M Nair +8 more
doaj +1 more source
They Can't Have My Embryo: The Ethics of Conditional Embryo Donation [PDF]
, 2013 There are substantial numbers of frozen embryos in storage that will not be used by those who produced them for their own fertility treatment. One option for such embryos is to donate them to others to use in their fertility treatment.
Eric Blyth +4 more
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Embryo donation parents' attitudes towards donors : comparison with adoption [PDF]
, 2008 BACKGROUND: Embryo donation produces a family structure where neither rearing parent is genetically related to the child, as in adoption. It is not known how embryo donation parents view the donors compared with how adoptive parents view the birth ...
MacCallum, Fiona
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The chicken embryo and its micro environment during egg storage and early incubation [PDF]
, 2008 When egg storage periods are prolonged (>7 days), hatchability and chick quality declines. The reason for this decline has been investigated, but is still not completely understood.
Brand, H., van den +3 more
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The first non-mammalian synapsid embryo from the Triassic of South Africa
PLoS ONEOviparity was likely the plesiomorphic reproductive condition for non-mammalian Synapsida, the stem-mammal group. Yet, despite nearly two centuries of research, no definitive fossil eggs of late Palaeozoic or early Mesozoic synapsids have been discovered.
Julien Benoit +2 more
doaj +2 more sources
Parenting and child development in families with a child conceived through embryo donation [PDF]
, 2007 Concerns have been raised regarding the potentially negative effects of conception using donated embryos on parenting and child development. Findings are presented of an exploratory study of families with a child conceived through embryo donation. Twenty-
Brinsden, Peter +2 more
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Studies on nonmammalian nephrons [PDF]
, 1982 The number of studies with segments of renal tubules from nonmammalian vertebrates isolated and perfused in vitro has increased substantially in recent years. These studies involve renal tubules from fish, amphibians, and reptiles.
Dantzler, William H. +1 more
core +1 more source
Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases
Molecular Imaging, 2018 Metastasis is the most common cause of death for patients with cancer. To fully understand the steps involved in metastatic dissemination, in vivo models are required, of which murine ones are the most common.
Anne Herrmann PhD +4 more
doaj +1 more source
Embryo donation families : a follow-up in middle childhood [PDF]
, 2007 Couples who conceive using donated embryos rear a child to whom they are genetically unrelated. It has been suggested that this may have negative consequences for parenting and child development.
Boivin, Jacky +3 more
core +1 more source