Results 41 to 50 of about 9,662 (120)

The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 6, Page 325-340, September 2025.
The main stages of development during which species‐specific heart anatomy is determined in the ontogeny of representative tetrapods. Transcriptomic similarity is expected earlier in development before heart anatomy diverges. ABSTRACT The tetrapod heart is characterized by three chambers in amphibians and non‐avian reptiles, as opposed to four in birds,
G. A. Cordero   +10 more
wiley   +1 more source

Propagação in vitro e caracterização molecular de porta-enxertos de Prunus por marcadores microssatelites (SSR) [PDF]

open access: yes, 2004
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias. Programa de Pós-Graduação em Recursos Genéticos Vegetais.A cultura do pessegueiro apresenta uma substancial importância na economia agrícola das regiões Sul e ...
Teixeira, Paulo de Tarso Lima
core  

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

Enigmatic Nodal and Lefty gene repertoire discrepancy: Latent evolutionary history revealed by vertebrate‐wide phylogeny

open access: yesDevelopmental Dynamics, Volume 254, Issue 8, Page 887-901, August 2025.
Abstract Homology in vertebrate body plans is traditionally ascribed to the high‐level conservation of regulatory components within the genetic programs governing them, particularly during the “phylotypic stage.” However, advancements in embryology and molecular phylogeny have unveiled the dynamic nature of gene repertoires responsible for early ...
Shigehiro Kuraku
wiley   +1 more source

Genotoxicity of a mixture of three widely used herbicides in chick embryo B cells

open access: yes, 2004
The cytogenetic effects of a mixture of three herbicides in common use, namely molinate, 2,4-D and MCPA were evaluated in chick embryo B cells in vivo. This nonmammalian test system has been validated for both direct- and indirect-acting mutagens and may
E. Arias, Arias Elio
core  

The dark sides of the GPCR tree ‐ research progress on understudied GPCRs

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 14, Page 3109-3134, July 2025.
Abstract A large portion of the human GPCRome is still in the dark and understudied, consisting even of entire subfamilies of GPCRs such as odorant receptors, class A and C orphans, adhesion GPCRs, Frizzleds and taste receptors. However, it is undeniable that these GPCRs bring an untapped therapeutic potential that should be explored further.
Magdalena M. Scharf   +10 more
wiley   +1 more source

Functional studies of cytokines produced by Xenopus Lymphocytes following T cell mitogen stimulation [PDF]

open access: yes, 1992
In vitro culture conditions for the production and assay of T cell mitogen - induced culture supernatants have been investigated in an amphibian model system, the clawed toad, Xenopus.
Hoi-Jen Ho, Jocelyn
core  

The role of ryanodine receptors in development

open access: yes, 2011
PhDCalcium ions (Ca2+) are fundamental to the regulation of many cellular processes; however, the coordination of these signals during embryogenesis is not well understood.
Wu, Houdini Ho-Tin
core  

"Mechanisms of transcriptional regulation by Tbx1"

open access: yes, 2010
Deletion 22q11.2 syndrome (22q11DS) is the most common microdeletion syndrome in man, with an incidence of approximately 1:4000 live births (1); the major malformations include congenital heart defects such as truncus arteriosus (TA) and interrupted ...
Pane, Luna Simona
core  

Development and application of non-integrating lentiviral vectors for gene therapy

open access: yes, 2009
Lentiviruses stably integrate their genome into the host genome. Although this feature can be advantageous for long term transgene expression, it also has the potential to cause mutagenesis and cell transformation.
Apolonia, L.F.S.
core  

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